Genetics and Gene Editing Methods in


Journal

Cold Spring Harbor protocols
ISSN: 1559-6095
Titre abrégé: Cold Spring Harb Protoc
Pays: United States
ID NLM: 101524530

Informations de publication

Date de publication:
01 06 2023
Historique:
medline: 5 6 2023
pubmed: 26 10 2022
entrez: 25 10 2022
Statut: epublish

Résumé

Our understanding of biological systems has for many years been heavily influenced by experimental approaches that exploit genetic methods. These include gain-of-function experiments that overexpress transgenes or ectopically express injected RNA and loss-of-function experiments that knock out genes or knock down RNAs. Here, we review how these methods have been applied in

Identifiants

pubmed: 36283837
pii: pdb.top107045
doi: 10.1101/pdb.top107045
doi:

Substances chimiques

Xenopus Proteins 0
RNA 63231-63-0

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

pdb.top107045

Informations de copyright

© 2023 Cold Spring Harbor Laboratory Press.

Auteurs

Matthew Guille (M)

European Xenopus Resource Centre, School of Biological Sciences, University of Portsmouth, Portsmouth PO1 2UP, United Kingdom.

Robert Grainger (R)

Department of Biology, University of Virginia, Charlottesville, Virginia 22903, USA rmg9p@virginia.edu.

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Classifications MeSH