Pure lumbar foraminal cavernous malformation in a patient with Cowden syndrome-a case report.
Case report
Cowden syndrome (CS)
cavernous malformation (CM)
intra-foraminal tumor
nerve root sacrifice
Journal
Journal of spine surgery (Hong Kong)
ISSN: 2414-469X
Titre abrégé: J Spine Surg
Pays: China
ID NLM: 101685460
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
14
03
2022
accepted:
01
06
2022
entrez:
26
10
2022
pubmed:
27
10
2022
medline:
27
10
2022
Statut:
ppublish
Résumé
Spinal cavernous malformations (CMs) are slow flow venous vascular malformations which can occur in vertebral body, epidural space or intramedullary. Only 7 cases were described confined in foraminal space. Cowden syndrome (CS) is an autosomal dominant genodermatosis that may present and develop vascular malformations, which include CM. They were found intracranial, and rarely visceral. No association with spinal CM and CS has been reported to date. A 46-year-old patient with CS came to our attention with a L5 radiculopathy secondary to a slow-growing intra-foraminal mass lesion, with bony scalloping. The lesion mimicked a schwannoma at radiological imaging and intraoperative findings. CMs can be confined to foraminal space and associated with CS. They may mimic peripheral nerve sheath tumors. Diagnosis may be challenging. No pathognomonic imaging features were found. Complete resection with root sacrifice seems to be a safe and efficient technique.
Sections du résumé
Background
UNASSIGNED
Spinal cavernous malformations (CMs) are slow flow venous vascular malformations which can occur in vertebral body, epidural space or intramedullary. Only 7 cases were described confined in foraminal space. Cowden syndrome (CS) is an autosomal dominant genodermatosis that may present and develop vascular malformations, which include CM. They were found intracranial, and rarely visceral. No association with spinal CM and CS has been reported to date.
Case Description
UNASSIGNED
A 46-year-old patient with CS came to our attention with a L5 radiculopathy secondary to a slow-growing intra-foraminal mass lesion, with bony scalloping. The lesion mimicked a schwannoma at radiological imaging and intraoperative findings.
Conclusions
UNASSIGNED
CMs can be confined to foraminal space and associated with CS. They may mimic peripheral nerve sheath tumors. Diagnosis may be challenging. No pathognomonic imaging features were found. Complete resection with root sacrifice seems to be a safe and efficient technique.
Identifiants
pubmed: 36285093
doi: 10.21037/jss-22-21
pii: jss-08-03-390
pmc: PMC9547691
doi:
Types de publication
Case Reports
Langues
eng
Pagination
390-396Informations de copyright
2022 Journal of Spine Surgery. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jss.amegroups.com/article/view/10.21037/jss-22-21/coif). The authors have no conflicts of interest to declare.
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