Surveillance of Tahyna Orthobunyavirus in Urban Areas in Croatia-The "One Health" Approach.

Croatia One Health Tahyna orthobunyavirus horses humans mosquitoes pet animals

Journal

Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042

Informations de publication

Date de publication:
20 Oct 2022
Historique:
received: 07 10 2022
revised: 14 10 2022
accepted: 18 10 2022
entrez: 26 10 2022
pubmed: 27 10 2022
medline: 27 10 2022
Statut: epublish

Résumé

Tahyna orthobunyavirus (TAHV) is a neglected mosquito-borne bunyavirus. Although the virus is widespread in continental Europe, TAHV infections are rarely reported. We analyzed the prevalence of TAHV in humans and different animal species as well as mosquitoes collected in urban areas of Zagreb and its surroundings in the period from 2020 to 2022. The study included 32 patients with neuroinvasive disease (NID), 218 asymptomatic individuals, 98 horses, 94 pet animals (dogs and cats), and 4456 TAHV NT antibodies were detected in 3/9.4% of patients with NID, 8/3.7% of asymptomatic individuals, 29/29.6% of horses, and 11/11.7% of pet animals. There was no difference in the seroprevalence according to age, sex, and area of residence in asymptomatic individuals. In addition, TAHV seropositivity did not differ according to age and sex in pet animals. None of the tested mosquito pools was TAHV RNA-positive. The presented results highlight the importance of interdisciplinary surveillance ("One Health") of this neglected viral zoonosis.

Sections du résumé

BACKGROUND BACKGROUND
Tahyna orthobunyavirus (TAHV) is a neglected mosquito-borne bunyavirus. Although the virus is widespread in continental Europe, TAHV infections are rarely reported. We analyzed the prevalence of TAHV in humans and different animal species as well as mosquitoes collected in urban areas of Zagreb and its surroundings in the period from 2020 to 2022.
METHODS METHODS
The study included 32 patients with neuroinvasive disease (NID), 218 asymptomatic individuals, 98 horses, 94 pet animals (dogs and cats), and 4456
RESULTS RESULTS
TAHV NT antibodies were detected in 3/9.4% of patients with NID, 8/3.7% of asymptomatic individuals, 29/29.6% of horses, and 11/11.7% of pet animals. There was no difference in the seroprevalence according to age, sex, and area of residence in asymptomatic individuals. In addition, TAHV seropositivity did not differ according to age and sex in pet animals. None of the tested mosquito pools was TAHV RNA-positive.
CONCLUSIONS CONCLUSIONS
The presented results highlight the importance of interdisciplinary surveillance ("One Health") of this neglected viral zoonosis.

Identifiants

pubmed: 36288061
pii: tropicalmed7100320
doi: 10.3390/tropicalmed7100320
pmc: PMC9609863
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Croatian Science Foundation
ID : IP-2016-06-7456
Organisme : European Union's Horizon 2020 research
ID : 653316

Références

Acta Virol. 1975 Jul;19(4):349-53
pubmed: 241234
Padiatr Grenzgeb. 1980;19(1):11-23
pubmed: 7454370
Emerg Infect Dis. 2009 Feb;15(2):306-9
pubmed: 19193280
Microorganisms. 2022 Jul 18;10(7):
pubmed: 35889162
Folia Parasitol (Praha). 1978;25(2):187-90
pubmed: 28998
Biomed Environ Sci. 2015 May;28(5):374-7
pubmed: 26055565
Med Vet Entomol. 2019 Mar;33(1):171-176
pubmed: 30144125
Parasit Vectors. 2021 Oct 30;14(1):561
pubmed: 34717742
Zoonoses Public Health. 2018 Jun;65(4):459-463
pubmed: 29516663
Emerg Infect Dis. 2005 Jan;11(1):116-8
pubmed: 15705333
Acta Med Croatica. 1998;52(2):87-9
pubmed: 9682494
Vector Borne Zoonotic Dis. 2014 Apr;14(4):272-7
pubmed: 24689784
J Med Entomol. 2010 May;47(3):466-72
pubmed: 20496595
Am J Trop Med Hyg. 2010 Apr;82(4):705-11
pubmed: 20348523
Microbiol Spectr. 2022 Oct 26;10(5):e0158722
pubmed: 36165787
Vopr Virusol. 1994 Jul-Aug;39(4):190-1
pubmed: 7998402
Vector Borne Zoonotic Dis. 2011 Dec;11(12):1577-81
pubmed: 21867416
Vector Borne Zoonotic Dis. 2009 Jun;9(3):295-9
pubmed: 19534626
J Infect Dev Ctries. 2016 Dec 30;10(12):1286-1293
pubmed: 28036307
Virol Sin. 2018 Feb;33(1):5-20
pubmed: 29532388
Parasitol Res. 2008 Dec;103 Suppl 1:S29-43
pubmed: 19030884
J Med Entomol. 2014 Nov 1;51(6):1264-7
pubmed: 26309316
Vector Borne Zoonotic Dis. 2010 Nov;10(9):875-84
pubmed: 20370434
Viruses. 2021 Nov 22;13(11):
pubmed: 34835140
Am J Trop Med Hyg. 2016 Apr;94(4):794-9
pubmed: 26880770
Am J Trop Med Hyg. 2006 Jun;74(6):1078-83
pubmed: 16760524
Vet Med (Praha). 1993;38(6):375-9
pubmed: 8346623
Epidemiol Mikrobiol Imunol. 2004 Aug;53(3):112-20
pubmed: 15524269
Infect Genet Evol. 2021 Mar;88:104711
pubmed: 33421655
J Wildl Dis. 1993 Oct;29(4):572-6
pubmed: 8258856
Vet Med (Praha). 1992 Nov;37(11):633-6
pubmed: 1292172

Auteurs

Vladimir Stevanovic (V)

Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.

Tatjana Vilibic-Cavlek (T)

Department of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia.
Department of Microbiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.

Vladimir Savic (V)

Poultry Center, Croatian Veterinary Institute, 10000 Zagreb, Croatia.

Ana Klobucar (A)

Department of Epidemiology, Andrija Stampar Teaching Institute of Public Health, 10000 Zagreb, Croatia.

Snjezana Kovac (S)

Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.

Marcela Curman Posavec (M)

Department of Epidemiology, Andrija Stampar Teaching Institute of Public Health, 10000 Zagreb, Croatia.

Suncica Petrinic (S)

Department of Epidemiology, Andrija Stampar Teaching Institute of Public Health, 10000 Zagreb, Croatia.

Maja Bogdanic (M)

Department of Virology, Croatian Institute of Public Health, 10000 Zagreb, Croatia.

Marija Santini (M)

Department for Adult Intensive Care and Neuroinfections, University Hospital for Infectious Diseases "Dr. Fran Mihaljevic", 10000 Zagreb, Croatia.

Vanja Tesic (V)

Department of Epidemiology, Andrija Stampar Teaching Institute of Public Health, 10000 Zagreb, Croatia.
Department of Social Medicine and Epidemiology, Medical Faculty, University of Rijeka, 51000 Rijeka, Croatia.

Nathalia de Albuquerque Soares (N)

Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.

Ljubo Barbic (L)

Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia.

Classifications MeSH