Detection of Recurrence After Primary Treatment for Oropharyngeal Carcinoma.


Journal

Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988

Informations de publication

Date de publication:
Nov 2022
Historique:
received: 20 08 2022
revised: 07 09 2022
accepted: 09 09 2022
entrez: 26 10 2022
pubmed: 27 10 2022
medline: 29 10 2022
Statut: ppublish

Résumé

Post-treatment surveillance of patients with squamous cell oropharyngeal carcinoma (SCOPC) consists of routine follow-up visits for 5 years. It has been suggested that this program is inefficient for finding recurrences and increasing survival. The primary study objective was to investigate how recurrences after treatment for SCOPC were detected, i.e., at routine follow-up visits, at patient-initiated visits, or incidentally. The secondary objective was to investigate whether 2-year survival after diagnosis of recurrence depended on the manner of detection. Patients with recurrences from SCOPC between 1988 and 2018 were included. Survival was analysed by the Kaplan-Meier method with log-rank test. A total of 75 patients were included. Almost one-third were alive 2 years after the diagnosis of recurrence. Recurrences were detected at routine follow-up visits in 50.7%, at patient-initiated visits in 42.7% and 6.6% were found incidentally. There was an increased survival in the patient-initiated group, but this was not significant. The majority of recurrences in both groups compared were amenable to curative treatment.

Sections du résumé

BACKGROUND/AIM OBJECTIVE
Post-treatment surveillance of patients with squamous cell oropharyngeal carcinoma (SCOPC) consists of routine follow-up visits for 5 years. It has been suggested that this program is inefficient for finding recurrences and increasing survival. The primary study objective was to investigate how recurrences after treatment for SCOPC were detected, i.e., at routine follow-up visits, at patient-initiated visits, or incidentally. The secondary objective was to investigate whether 2-year survival after diagnosis of recurrence depended on the manner of detection.
PATIENTS AND METHODS METHODS
Patients with recurrences from SCOPC between 1988 and 2018 were included. Survival was analysed by the Kaplan-Meier method with log-rank test.
RESULTS RESULTS
A total of 75 patients were included. Almost one-third were alive 2 years after the diagnosis of recurrence. Recurrences were detected at routine follow-up visits in 50.7%, at patient-initiated visits in 42.7% and 6.6% were found incidentally. There was an increased survival in the patient-initiated group, but this was not significant.
CONCLUSION CONCLUSIONS
The majority of recurrences in both groups compared were amenable to curative treatment.

Identifiants

pubmed: 36288847
pii: 42/11/5597
doi: 10.21873/anticanres.16067
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5597-5600

Informations de copyright

Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Auteurs

Fredrik Landström (F)

Department of Otolaryngology, Örebro University Hospital, Örebro University, Örebro, Sweden; fredrik.landstrom@regionorebrolan.se.
Örebro University, Örebro, Sweden.

Johan Reizenstein (J)

Department of Oncology, Örebro University Hospital, Örebro, Sweden.

Stefan Kristiansson (S)

Department of Otolaryngology, Örebro University Hospital, Örebro University, Örebro, Sweden.

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Classifications MeSH