Tunisian Multicenter Study on the Prevalence of Colistin Resistance in Clinical Isolates of Gram Negative Bacilli: Emergence of

Gram negative bacteria colistin resistance mcr-1 gene multi-drug resistant bacteria

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
11 Oct 2022
Historique:
received: 19 08 2022
revised: 12 09 2022
accepted: 02 10 2022
entrez: 27 10 2022
pubmed: 28 10 2022
medline: 28 10 2022
Statut: epublish

Résumé

Actually, no data on the prevalence of plasmid colistin resistance in Tunisia are available among clinical bacteria. This study aimed to investigate the current epidemiology of colistin resistance and the spread of the A total of 836 GNB strains were inoculated on COL-R agar plates with selective screening agar for the isolation of GNB resistant to colistin. For the selected isolates, Colistin-resistance was detected in 5.02% (42/836) of the isolates and colistin-resistant isolates harboured an ESBL ( This study reports the first description of the

Sections du résumé

BACKGROUND BACKGROUND
Actually, no data on the prevalence of plasmid colistin resistance in Tunisia are available among clinical bacteria.
OBJECTIVES OBJECTIVE
This study aimed to investigate the current epidemiology of colistin resistance and the spread of the
METHODS METHODS
A total of 836 GNB strains were inoculated on COL-R agar plates with selective screening agar for the isolation of GNB resistant to colistin. For the selected isolates,
RESULTS RESULTS
Colistin-resistance was detected in 5.02% (42/836) of the isolates and colistin-resistant isolates harboured an ESBL (
THE CONCLUSIONS CONCLUSIONS
This study reports the first description of the

Identifiants

pubmed: 36290048
pii: antibiotics11101390
doi: 10.3390/antibiotics11101390
pmc: PMC9598684
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Sana Ferjani (S)

Faculty of Medicine of Tunis, University of Tunis El Manar, LR99ES09, Tunis Rue Djebal Lakhdar 1006, Tunisia.

Elaa Maamar (E)

Faculty of Medicine of Tunis, University of Tunis El Manar, LR99ES09, Tunis Rue Djebal Lakhdar 1006, Tunisia.

Asma Ferjani (A)

Faculty of Medicine of Tunis, University of Tunis El Manar, LR99ES09, Tunis Rue Djebal Lakhdar 1006, Tunisia.
Charles Nicolle Hospital, Laboratory of Microbiology, Boulevard 9 April, Tunis 1006, Tunisia.

Khaoula Meftah (K)

Laboratory of Microbiology, Children's Hospital of Tunis, Boulevard 9 April, Tunis 1006, Tunisia.

Hager Battikh (H)

Microbiology Laboratory, Rabta University Hospital, Rue Jabbari, Tunis 1007, Tunisia.

Besma Mnif (B)

Laboratory of Microbiology, Habib Bourguiba University Hospital, Route de l'Ain, Sfax 3000, Tunisia.
Research Laboratory for Microorganisms and Human Disease, University of Sfax, Avenue Majida Boulila, Sfax 3029, Tunisia.

Manel Hamdoun (M)

Aziza Othmana Hospital, Laboratoire de Microbiologie-Biochimie, Bab Menara Tunis 1008, Tunisia.
Faculty of Medicine of Tunis, University of Tunis El Manar, LR16SP01, Tunis Rue Djebal Lakhdar 1006, Tunisia.

Yosra Chebbi (Y)

National Bone Marrow Transplant Center, Laboratory Ward, Tunis Rue Djebal Lakhdar 1006, Tunisia.
Faculty of Medicine of Tunis, Tunis El Manar University, LR18ES39, Tunis Rue Djebal Lakhdar 1006, Tunisia.

Lamia Kanzari (L)

Faculty of Medicine of Tunis, University of Tunis El Manar, LR99ES09, Tunis Rue Djebal Lakhdar 1006, Tunisia.
Charles Nicolle Hospital, Laboratory of Microbiology, Boulevard 9 April, Tunis 1006, Tunisia.

Wafa Achour (W)

National Bone Marrow Transplant Center, Laboratory Ward, Tunis Rue Djebal Lakhdar 1006, Tunisia.
Faculty of Medicine of Tunis, Tunis El Manar University, LR18ES39, Tunis Rue Djebal Lakhdar 1006, Tunisia.

Olfa Bahri (O)

Aziza Othmana Hospital, Laboratoire de Microbiologie-Biochimie, Bab Menara Tunis 1008, Tunisia.
Faculty of Medicine of Tunis, University of Tunis El Manar, LR16SP01, Tunis Rue Djebal Lakhdar 1006, Tunisia.

Adenene Hammami (A)

Laboratory of Microbiology, Habib Bourguiba University Hospital, Route de l'Ain, Sfax 3000, Tunisia.
Research Laboratory for Microorganisms and Human Disease, University of Sfax, Avenue Majida Boulila, Sfax 3029, Tunisia.

Meriam Zribi (M)

Microbiology Laboratory, Rabta University Hospital, Rue Jabbari, Tunis 1007, Tunisia.

Hanen Smaoui (H)

Laboratory of Microbiology, Children's Hospital of Tunis, Boulevard 9 April, Tunis 1006, Tunisia.

Ilhem Boutiba-Ben Boubaker (IB)

Faculty of Medicine of Tunis, University of Tunis El Manar, LR99ES09, Tunis Rue Djebal Lakhdar 1006, Tunisia.
Charles Nicolle Hospital, Laboratory of Microbiology, Boulevard 9 April, Tunis 1006, Tunisia.

Classifications MeSH