Profiles of Caregiver-Reported Executive Function in Children with Down Syndrome.
Down syndrome
executive function
latent profile analysis
Journal
Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646
Informations de publication
Date de publication:
01 Oct 2022
01 Oct 2022
Historique:
received:
01
08
2022
revised:
14
09
2022
accepted:
22
09
2022
entrez:
27
10
2022
pubmed:
28
10
2022
medline:
28
10
2022
Statut:
epublish
Résumé
Children with Down syndrome (DS) are at risk for challenges with aspects of executive function (EF). The current study explores whether heterogeneity in EF profiles can be detected within a sample of children with DS. Participants were 69 children with DS, ages 3-10 years (M = 6.23, SD = 1.91). T-scores from a caregiver-report measure of executive function were modeled using latent profile analysis, and auxiliary analyses examined the association between demographic and biomedical factors and probability of profile membership. The two-profile solution was the best fit for the sample, with a profile that involved elevated scores in working memory only ("Working Memory Only" profile; 43% of sample) and a "Multi-Domain" profile that involved elevated scores in planning, inhibition, and working memory (57%). The presence of congenital heart defects was associated with a higher probability of assignment to the Multi-Domain profile. Findings from this study contribute to the characterization of heterogeneous outcomes associated with DS.
Identifiants
pubmed: 36291267
pii: brainsci12101333
doi: 10.3390/brainsci12101333
pmc: PMC9599143
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NICHD NIH HHS
ID : R21 HD101000
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002535
Pays : United States
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : R01HD099150-03S1
Organisme : NICHD NIH HHS
ID : R01 HD099150
Pays : United States
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : R01HD088409
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : P50HD103526
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : 1R01HD093754-01A1
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : R01HD099150-0
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : R21 HD101000-01
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