Hypersensitivity to Intravenous Iron Preparations.
desensitization
drug allergy
drug provocation test
hypersensitivity reaction
iron
iron hypersensitivity
Journal
Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936
Informations de publication
Date de publication:
27 Sep 2022
27 Sep 2022
Historique:
received:
09
08
2022
revised:
10
09
2022
accepted:
15
09
2022
entrez:
27
10
2022
pubmed:
28
10
2022
medline:
28
10
2022
Statut:
epublish
Résumé
Intravenous iron is widely used for the treatment of iron deficiency anemia when adherence to oral iron replacement is poor. Acute hypersensitivity reactions during iron infusions are very rare but can be life threatening. Major risk factors for hypersensitivity reactions include a previous reaction to an iron infusion, a fast iron infusion rate, multiple drug allergies, atopic diseases, high serum tryptase levels, asthma, and urticaria. The management of iron infusions requires meticulous observation, and, in the event of an adverse reaction, prompt recognition and severity-related interventions by well-trained medical and nursing staff. Avoidance of IV iron products in patients with iron hypersensitivity reactions may not be considered as a standard practice.
Identifiants
pubmed: 36291409
pii: children9101473
doi: 10.3390/children9101473
pmc: PMC9600424
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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