Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population.
InDels
Investigator DIPplex
Poland
forensic genetics
population
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
20 Sep 2022
20 Sep 2022
Historique:
received:
30
08
2022
accepted:
16
09
2022
entrez:
27
10
2022
pubmed:
28
10
2022
medline:
29
10
2022
Statut:
epublish
Résumé
(1) Background: Insertion-deletion (InDel) markers show the advantages of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) and are considered alternative markers in forensic genetics. (2) Methods: Allelic frequencies and corresponding forensic efficiency parameters of 30 autosomal polymorphic InDel loci included in the Investigator DIPplex kit (Qiagen) were obtained in a sample of 631 unrelated Polish individuals. Allelic frequency data were compared with those reported for selected populations (3) Results: All the loci conformed with Hardy-Weinberg equilibrium after applying a Bonferroni correction and no pair-wise significant linkage disequilibrium was detected. (4) Conclusions: DIPplex Kit differences were high among populations worldwide. The InDel markers are highly discriminating for human identification purposes in the Polish population.
Identifiants
pubmed: 36292568
pii: genes13101683
doi: 10.3390/genes13101683
pmc: PMC9601377
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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