Venous Wall of Patients with Chronic Venous Disease Exhibits a Glycolytic Phenotype.
chronic venous disease (CVeD)
glycolytic phenotype
histopathological markers
varicose veins (VVs)
Journal
Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269
Informations de publication
Date de publication:
03 Oct 2022
03 Oct 2022
Historique:
received:
10
08
2022
revised:
14
09
2022
accepted:
29
09
2022
entrez:
27
10
2022
pubmed:
28
10
2022
medline:
28
10
2022
Statut:
epublish
Résumé
Chronic venous disease (CVeD) is a rising medical condition characterized by a broad spectrum of disorders in the venous system. Varicose veins (VVs) represent a frequent clinical manifestation of CVeD, particularly in the lower limbs. Prior histopathological studies have defined a set of alterations observed in the venous wall of patients with VVs, affecting their structure and behavior. Metabolic changes in the veins appear to be a critical biological mechanism aiding our understanding of the pathogenesis of CVeD. In this sense, previous studies have identified a potential role of a glycolytic phenotype in the development of different vascular disorders; however, its precise role in CVeD remains to be fully explored. Thus, the aim of the present study was to analyze the gene and protein expression of glucose transporter 1 (GLUT-1) and the glycolytic enzymes PGK-1, ALD, GA3PDH and LDH in the VVs of patients with CVeD (
Identifiants
pubmed: 36294781
pii: jpm12101642
doi: 10.3390/jpm12101642
pmc: PMC9604927
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Comunidad de Madrid
ID : MITIC-CM
Références
Phlebology. 2012 Dec;27(8):416-22
pubmed: 22345329
Int J Mol Sci. 2018 Jun 05;19(6):
pubmed: 29874834
Acta Pharmacol Sin. 2022 Feb;43(2):251-259
pubmed: 33850277
Annu Rev Physiol. 2019 Feb 10;81:483-503
pubmed: 30742787
Histol Histopathol. 2021 May;36(5):547-558
pubmed: 33645625
Biomed Res Int. 2020 Dec 14;2020:6782659
pubmed: 33381575
World J Surg. 2003 Aug;27(8):901-5
pubmed: 12784143
Int Angiol. 2014 Jun;33(3):212-21
pubmed: 24755829
Circ Res. 2006 Jul 21;99(2):191-200
pubmed: 16778134
Phlebology. 2016 Mar;31(1 Suppl):74-9
pubmed: 26916773
Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):86-94
pubmed: 20947823
J Int Med Res. 2021 Sep;49(9):3000605211041275
pubmed: 34590920
J Investig Med. 2019 Dec;67(8):1149-1154
pubmed: 31427387
J Oral Maxillofac Pathol. 2019 Sep-Dec;23(3):443-449
pubmed: 31942129
Oxid Med Cell Longev. 2018 Sep 3;2018:3974026
pubmed: 30250632
Kaohsiung J Med Sci. 2013 Nov;29(11):594-605
pubmed: 24183353
J Vasc Surg Venous Lymphat Disord. 2020 May;8(3):342-352
pubmed: 32113854
J Vasc Surg. 2013 Apr;57(4 Suppl):37S-45S
pubmed: 23522716
J Oncol. 2018 Oct 16;2018:3812581
pubmed: 30410539
Front Cell Dev Biol. 2021 Feb 18;9:626047
pubmed: 33681205
J Clin Med. 2021 Jul 22;10(15):
pubmed: 34362022
J Vasc Surg. 2012 May;55(5):1427-39
pubmed: 22277691
Mol Cell. 2019 Nov 7;76(3):516-527.e7
pubmed: 31492635
J Comp Eff Res. 2020 Dec;9(17):1205-1218
pubmed: 33079592
Eur J Vasc Endovasc Surg. 2012 Apr;43(4):480-4
pubmed: 22289612
Semin Vasc Surg. 2021 Mar;34(1):59-64
pubmed: 33757637
Int J Med Sci. 2022 Jan 1;19(1):186-194
pubmed: 34975312
Maedica (Bucur). 2017 Jan;12(1):59-61
pubmed: 28878840
J Appl Physiol (1985). 2000 Apr;88(4):1474-80
pubmed: 10749844
Cell. 2016 Jan 28;164(3):433-46
pubmed: 26824656
Int J Med Sci. 2021 Mar 3;18(9):1921-1934
pubmed: 33850461
Biotechniques. 2004 Aug;37(2):226-31
pubmed: 15335214
Pathology. 2010;42(5):446-53
pubmed: 20632821
Mol Med Rep. 2018 Aug;18(2):1710-1717
pubmed: 29845198
Eur J Vasc Endovasc Surg. 2015 Apr;49(4):432-9
pubmed: 25701071
Am J Prev Med. 1988 Mar-Apr;4(2):96-101
pubmed: 3395496
BMC Bioinformatics. 2012 Jun 18;13:134
pubmed: 22708584
Sci Rep. 2017 Jun 7;7(1):2989
pubmed: 28592827
Immunometabolism. 2021 May 17;3(3):e210020
pubmed: 34084561
Pharmaceutics. 2020 May 02;12(5):
pubmed: 32370188
J Cell Mol Med. 2020 Apr;24(7):4157-4170
pubmed: 32141705
J Pers Med. 2022 Feb 10;12(2):
pubmed: 35207748
Am J Physiol Heart Circ Physiol. 2020 Sep 1;319(3):H613-H631
pubmed: 32762559
Oxid Med Cell Longev. 2018 Jul 2;2018:1495170
pubmed: 30057669
Int Angiol. 2012 Apr;31(2):105-15
pubmed: 22466974
J Physiol. 2021 Jan;599(1):23-37
pubmed: 33006160
Circ Res. 2017 Nov 10;121(11):1251-1262
pubmed: 29021296
Biomedicines. 2021 Feb 03;9(2):
pubmed: 33546224
Eur J Vasc Endovasc Surg. 2017 Dec;54(6):752-758
pubmed: 29031868
Biomed Res Int. 2018 Oct 18;2018:7156150
pubmed: 30498761
J Vasc Res. 2007;44(3):192-201
pubmed: 17337905
J Vasc Surg. 2007 Aug;46(2):331-7
pubmed: 17600666
Adv Ther. 2019 Mar;36(Suppl 1):5-12
pubmed: 30758738
Leukemia. 2015 May;29(5):1163-76
pubmed: 25394713
Yeungnam Univ J Med. 2021 Jul;38(3):183-193
pubmed: 33596629
J Cell Physiol. 2007 May;211(2):477-85
pubmed: 17167776
Med Clin (Barc). 2017 Apr 21;148(8):371-376
pubmed: 28168973