Alpha-Phellandrene and Alpha-Phellandrene-Rich Essential Oils: A Systematic Review of Biological Activities, Pharmaceutical and Food Applications.
alpha-phellandrene
antimicrobial
antitumoral
food-borne pathogens
insecticidal
Journal
Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444
Informations de publication
Date de publication:
14 Oct 2022
14 Oct 2022
Historique:
received:
09
09
2022
revised:
06
10
2022
accepted:
11
10
2022
entrez:
27
10
2022
pubmed:
28
10
2022
medline:
28
10
2022
Statut:
epublish
Résumé
Alpha-phellandrene is a very common cyclic monoterpene found in several EOs, which shows extensive biological activities. Therefore, the main focus of the present systematic review was to provide a comprehensive and critical analysis of the state of the art regarding its biological activities and pharmaceutical and food applications. In addition, the study identified essential oils rich in alpha-phellandrene and summarized their main biological activities as a preliminary screening to encourage subsequent studies on their single components. With this review, we selected and critically analyzed 99 papers, using the following bibliographic databases: PubMed, SciELO, Wiley and WOS, on 8 July 2022. Data were independently extracted by four authors of this work, selecting those studies which reported the keyword "alpha-phellandrene" in the title and/or the abstract, and avoiding those in which there was not a clear correlation between the molecule and its biological activities and/or a specific concentration from its source. Duplication data were removed in the final article. Many essential oils have significant amounts of alpha-phellandrene, and the species
Identifiants
pubmed: 36295037
pii: life12101602
doi: 10.3390/life12101602
pmc: PMC9605662
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
J Agric Food Chem. 2001 Jan;49(1):239-44
pubmed: 11170583
Food Chem. 2016 Apr 1;196:242-50
pubmed: 26593489
Nat Prod Res. 2018 May;32(9):1118-1122
pubmed: 28906143
Chem Biodivers. 2017 Apr;14(4):
pubmed: 27685082
Biomed Res Int. 2018 Oct 2;2018:6860271
pubmed: 30386794
Plants (Basel). 2022 Jan 31;11(3):
pubmed: 35161379
Galen Med J. 2019 Aug 16;8:e1532
pubmed: 34466524
Chem Biodivers. 2019 Dec;16(12):e1900434
pubmed: 31587473
Nat Prod Res. 2017 Nov;31(22):2654-2659
pubmed: 28278624
Antibiotics (Basel). 2021 Jan 01;10(1):
pubmed: 33401436
Am J Chin Med. 2015;43(1):121-36
pubmed: 25649747
Chem Biodivers. 2013 Nov;10(11):2061-77
pubmed: 24243615
Plants (Basel). 2021 Oct 15;10(10):
pubmed: 34686003
Nat Prod Res. 2016 Aug;30(16):1875-9
pubmed: 27498832
Plants (Basel). 2022 Aug 18;11(16):
pubmed: 36015446
Anticancer Res. 2014 Aug;34(8):4161-80
pubmed: 25075043
Food Chem. 2016 Feb 1;192:849-56
pubmed: 26304420
Ecotoxicol Environ Saf. 2018 Jul 30;156:263-270
pubmed: 29554611
J Med Entomol. 2007 May;44(3):524-9
pubmed: 17547241
Fish Shellfish Immunol. 2019 Jan;84:1108-1114
pubmed: 30414490
Nutr Cancer. 2014;66(6):970-9
pubmed: 25077527
Parasite. 2021;28:42
pubmed: 33944775
J Ethnopharmacol. 2014;151(1):485-92
pubmed: 24231069
Molecules. 2020 Dec 25;26(1):
pubmed: 33375652
Nat Prod Res. 2012 Nov;26(21):2030-4
pubmed: 22054412
J Intercult Ethnopharmacol. 2015 Jul-Sep;4(3):256-63
pubmed: 26401417
Chem Biodivers. 2019 Nov;16(11):e1900388
pubmed: 31475446
J Pharm Pharmacol. 2012 Feb;64(2):283-92
pubmed: 22221105
J Complement Integr Med. 2019 May 25;16(4):
pubmed: 31129652
Plant Physiol. 2009 Oct;151(2):925-35
pubmed: 19692533
Pest Manag Sci. 2013 Nov;69(11):1267-71
pubmed: 23526766
Food Chem Toxicol. 2011 Oct;49(10):2471-94
pubmed: 21726592
Nat Prod Res. 2007 May;21(5):412-7
pubmed: 17487612
Foods. 2020 Mar 21;9(3):
pubmed: 32245234
J Ethnopharmacol. 2021 Oct 5;278:114205
pubmed: 34000364
Oxid Med Cell Longev. 2019 Feb 7;2019:6587150
pubmed: 30881596
Syst Rev. 2021 Mar 29;10(1):89
pubmed: 33781348
Molecules. 2021 Jan 26;26(3):
pubmed: 33530290
Foods. 2016 May 25;5(2):
pubmed: 28231136
J Med Entomol. 2020 Feb 27;57(2):627-630
pubmed: 31637445
Environ Sci Pollut Res Int. 2018 Mar;25(7):6466-6473
pubmed: 29250730
J Med Food. 2016 Mar;19(3):266-73
pubmed: 26836214
J Food Sci Technol. 2018 Apr;55(4):1582-1590
pubmed: 29606774
J Med Food. 2006 Winter;9(4):552-61
pubmed: 17201644
J Microbiol Biotechnol. 2017 Mar 28;27(3):429-438
pubmed: 27994215
Molecules. 2020 Jul 31;25(15):
pubmed: 32751878
Nat Prod Res. 2022 Jul;36(14):3587-3597
pubmed: 33410338
PLoS One. 2015 Dec 09;10(12):e0144586
pubmed: 26650757
Biomed Pharmacother. 2022 Oct;154:113559
pubmed: 35994817
Pestic Biochem Physiol. 2019 Jan;153:17-27
pubmed: 30744891
Exp Appl Acarol. 2015 Dec;67(4):595-606
pubmed: 26385208
Int J Mol Sci. 2020 Jun 10;21(11):
pubmed: 32532055
Pest Manag Sci. 2021 Nov;77(11):5255-5267
pubmed: 34310838
Medicines (Basel). 2015 Dec 29;3(1):
pubmed: 28930111
J Biomed Sci. 2019 Jan 9;26(1):5
pubmed: 30621719
Braz J Microbiol. 2014 Oct 09;45(3):821-8
pubmed: 25477913
BMC Complement Altern Med. 2013 Oct 14;13:265
pubmed: 24119438
Food Chem. 2021 May 15;344:128707
pubmed: 33267985
BMC Complement Altern Med. 2014 Apr 04;14:125
pubmed: 24708588
Int J Mol Sci. 2020 Dec 17;21(24):
pubmed: 33348921
Phytochemistry. 2004 Aug;65(16):2411-3
pubmed: 15381015
Ecotoxicol Environ Saf. 2019 Apr 30;171:863-870
pubmed: 30665103
Int J Microbiol. 2017;2017:8761610
pubmed: 28127308
Molecules. 2017 Jul 12;22(7):
pubmed: 28704964
Chem Biodivers. 2020 Nov;17(11):e2000388
pubmed: 33063941
Photochem Photobiol. 2017 Jul;93(4):1063-1072
pubmed: 28178379
J Asian Nat Prod Res. 2021 Oct;23(10):938-954
pubmed: 33111547
Chem Biodivers. 2020 Dec;17(12):e2000561
pubmed: 33095499
Chem Biodivers. 2015 Oct;12(10):1565-74
pubmed: 26460561
J Sci Food Agric. 2018 Feb;98(3):833-848
pubmed: 28758221
J Agric Food Chem. 2015 Nov 18;63(45):9977-86
pubmed: 26500081
Acta Biochim Pol. 2014;61(1):41-6
pubmed: 24644552
Nat Prod Res. 2022 Feb;36(3):789-797
pubmed: 32820648
Evid Based Complement Alternat Med. 2021 Mar 15;2021:6643765
pubmed: 33790979
Parasitol Res. 2015 Sep;114(9):3385-91
pubmed: 26091760
Food Chem Toxicol. 2011 May;49(5):1188-92
pubmed: 21354246
J Food Sci. 2010 Aug 1;75(6):C466-72
pubmed: 20722898
Pestic Biochem Physiol. 2017 Jun;139:17-23
pubmed: 28595917
Environ Toxicol. 2015 Nov;30(11):1322-30
pubmed: 24861204
In Vivo. 2013 Nov-Dec;27(6):809-14
pubmed: 24292586
J Equine Vet Sci. 2022 Mar;110:103840
pubmed: 34923074
J Med Entomol. 2006 Jan;43(1):113-9
pubmed: 16506457
Microb Pathog. 2018 Jul;120:119-127
pubmed: 29704984
Int J Food Microbiol. 2008 Jul 31;125(3):242-51
pubmed: 18511141
Phytother Res. 2008 Mar;22(3):372-5
pubmed: 18058989
In Vivo. 2014 Jul-Aug;28(4):583-8
pubmed: 24982226
Nat Prod Res. 2020 Feb;34(4):545-548
pubmed: 30257572
Cancers (Basel). 2020 Sep 16;12(9):
pubmed: 32948083
J Med Entomol. 2015 Jan;52(1):93-100
pubmed: 26336285
Foods. 2021 Jan 21;10(2):
pubmed: 33494170
Pest Manag Sci. 2012 Nov;68(11):1492-500
pubmed: 22674887
Phytother Res. 2014 Oct;28(10):1423-46
pubmed: 24831562
Biomed Pharmacother. 2020 Sep;129:110402
pubmed: 32574969
Pest Manag Sci. 2015 Sep;71(9):1213-8
pubmed: 25204729
Contact Dermatitis. 2016 Sep;75(3):129-43
pubmed: 27173437
J Sci Food Agric. 2013 Mar 30;93(5):1112-8
pubmed: 22936395
Toxicol Appl Pharmacol. 2021 May 1;418:115497
pubmed: 33744277
Environ Toxicol. 2016 Nov;31(11):1640-1651
pubmed: 26174008