Anti-Aging and Neuroprotective Properties of

Drosophila melanogaster Grifola frondosa Hericium erinaceus Parkinson’s disease (PD) Saccharomyces cerevisiae medicinal mushrooms α-synuclein

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
18 Oct 2022
Historique:
received: 15 09 2022
revised: 12 10 2022
accepted: 14 10 2022
entrez: 27 10 2022
pubmed: 28 10 2022
medline: 29 10 2022
Statut: epublish

Résumé

Nutrition has relevant consequences for human health and increasing pieces of evidence indicate that medicinal mushrooms have several beneficial effects. One of the main issues in Western countries is represented by the challenges of aging and age-related diseases, such as neurodegenerative disorders. Among these, Parkinson's disease (PD) affects 10 million people worldwide and is associated with α-synuclein misfolding, also found in other pathologies collectively called synucleinopathies. Here, we show that aqueous extracts of two edible mushrooms,

Identifiants

pubmed: 36297052
pii: nu14204368
doi: 10.3390/nu14204368
pmc: PMC9611596
pii:
doi:

Substances chimiques

alpha-Synuclein 0
beta-Glucans 0
Heat-Shock Proteins 0
Protein Aggregates 0
Reactive Oxygen Species 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Italian Ministry of University and Research (MUR)
ID : Dipartimenti di Eccellenza 2017
Organisme : talian Ministry of University and Research (MUR)
ID : Fondo di Ricerca e Giovani
Organisme : Fondazione Umberto Veronesi
ID : fellowship
Organisme : Italian Ministry of University and Research (MUR)
ID : PhD fellowship

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Auteurs

Farida Tripodi (F)

Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.

Ermelinda Falletta (E)

Department of Chemistry, University of Milano, 20133 Milano, Italy.

Manuela Leri (M)

Department of Experimental and Clinical Biomedical Sciences, University of Firenze, 50134 Firenze, Italy.

Cristina Angeloni (C)

Department for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 47921 Rimini, Italy.

Daniela Beghelli (D)

School of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino (MC), Italy.

Laura Giusti (L)

School of Pharmacy, University of Camerino, 62032 Camerino (MC), Italy.

Riccardo Milanesi (R)

Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.

Belém Sampaio-Marques (B)

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.

Paula Ludovico (P)

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal.
ICVS/3B's-PT Government Associate Laboratory, 4806-909 Braga/Guimarães, Portugal.

Lorenzo Goppa (L)

Department of Earth and Environmental Sciences (DSTA), University of Pavia, 27100 Pavia, Italy.

Paola Rossi (P)

Department of Biology and Biotechnology "L. Spallanzani" (DBB), University of Pavia, 27100 Pavia, Italy.

Elena Savino (E)

Department of Earth and Environmental Sciences (DSTA), University of Pavia, 27100 Pavia, Italy.

Monica Bucciantini (M)

Department of Experimental and Clinical Biomedical Sciences, University of Firenze, 50134 Firenze, Italy.

Paola Coccetti (P)

Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.

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Classifications MeSH