Serendipitous Discovery of a Competitive Inhibitor of FraB, a

Salmonella deglycase competitive inhibitor drug discovery serendipity

Journal

Pathogens (Basel, Switzerland)
ISSN: 2076-0817
Titre abrégé: Pathogens
Pays: Switzerland
ID NLM: 101596317

Informations de publication

Date de publication:
26 Sep 2022
Historique:
received: 08 08 2022
revised: 18 09 2022
accepted: 20 09 2022
entrez: 27 10 2022
pubmed: 28 10 2022
medline: 28 10 2022
Statut: epublish

Résumé

Although salmonellosis, an infectious disease, is a significant global healthcare burden, there are no

Identifiants

pubmed: 36297159
pii: pathogens11101102
doi: 10.3390/pathogens11101102
pmc: PMC9609667
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : P41 GM128577
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI140541
Pays : United States
Organisme : NIH HHS
ID : NIAID AI140541
Pays : United States

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Auteurs

Pankajavalli Thirugnanasambantham (P)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.

Sravya Kovvali (S)

Department of Microbiology, The Ohio State University, Columbus, OH 43210, USA.

Austin Cool (A)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.

Yuan Gao (Y)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Resource for Native Mass Spectrometry-Guided Structural Biology, The Ohio State University, Columbus, OH 43210, USA.

Anice Sabag-Daigle (A)

Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210, USA.

Erin F Boulanger (EF)

Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210, USA.

Mark Mitton-Fry (M)

Department of Medicinal Chemistry and Pharmacognosy, The Ohio State University, Columbus, OH 43210, USA.

Angela Di Capua (AD)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Resource for Native Mass Spectrometry-Guided Structural Biology, The Ohio State University, Columbus, OH 43210, USA.

Edward J Behrman (EJ)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.

Vicki H Wysocki (VH)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Resource for Native Mass Spectrometry-Guided Structural Biology, The Ohio State University, Columbus, OH 43210, USA.

Steffen Lindert (S)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.

Brian M M Ahmer (BMM)

Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210, USA.

Venkat Gopalan (V)

Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Department of Microbiology, The Ohio State University, Columbus, OH 43210, USA.

Classifications MeSH