Learning the Hidden Signature of Fetal Arch Anatomy: a Three-Dimensional Shape Analysis in Suspected Coarctation of the Aorta.
Clinical Biomarker
Computational Anatomy
Congenital Heart Disease
Machine Learning
Magnetic Resonance Imaging
Statistical Shape Modeling
Journal
Journal of cardiovascular translational research
ISSN: 1937-5395
Titre abrégé: J Cardiovasc Transl Res
Pays: United States
ID NLM: 101468585
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
received:
09
06
2022
accepted:
13
10
2022
medline:
29
6
2023
pubmed:
28
10
2022
entrez:
27
10
2022
Statut:
ppublish
Résumé
Neonatal coarctation of the aorta (CoA) is a common congenital heart defect. Its antenatal diagnosis remains challenging, and its pathophysiology is poorly understood. We present a novel statistical shape modeling (SSM) pipeline to study the role and predictive value of arch shape in CoA in utero. Cardiac magnetic resonance imaging (CMR) data of 112 fetuses with suspected CoA was acquired and motion-corrected to three-dimensional volumes. Centerlines from fetal arches were extracted and used to build a statistical shape model capturing relevant anatomical variations. A linear discriminant analysis was used to find the optimal axis between CoA and false positive cases. The CoA shape risk score classified cases with an area under the curve of 0.907. We demonstrate the feasibility of applying a SSM pipeline to three-dimensional fetal CMR data while providing novel insights into the anatomical determinants of CoA and the relevance of in utero arch anatomy for antenatal diagnosis of CoA.
Identifiants
pubmed: 36301513
doi: 10.1007/s12265-022-10335-9
pii: 10.1007/s12265-022-10335-9
pmc: PMC10299929
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
738-747Subventions
Organisme : British Heart Foundation
ID : FS/ICRF/22/26028
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 102431
Pays : United Kingdom
Organisme : British Heart Foundation
ID : TA/F/20/210021
Pays : United Kingdom
Organisme : Wellcome Trust
ID : WT203148/Z/16/Z
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Department of Health
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 209450/Z/17/Z
Pays : United Kingdom
Informations de copyright
© 2022. The Author(s).
Références
Heart. 2005 Nov;91(11):1495-502
pubmed: 16230458
Eur Heart J. 2020 Dec 21;41(48):4556-4564
pubmed: 32128588
J Am Soc Echocardiogr. 2019 Nov;32(11):1470-1476
pubmed: 31443942
Lancet. 2019 Apr 20;393(10181):1619-1627
pubmed: 30910324
Nat Commun. 2020 Oct 5;11(1):4992
pubmed: 33020487
Magn Reson Med. 2019 Sep;82(3):1055-1072
pubmed: 31081250
Heart. 2002 Jan;87(1):67-9
pubmed: 11751670
Ultrasound Obstet Gynecol. 2020 Dec;56(6):837-849
pubmed: 31909552
BMC Med Imaging. 2016 May 31;16(1):40
pubmed: 27245048
J Am Soc Echocardiogr. 2017 Jun;30(6):589-594
pubmed: 28410945
Neuroimage. 2006 Jul 1;31(3):1116-28
pubmed: 16545965
J Physiol Sci. 2017 Mar;67(2):259-270
pubmed: 28000176
Pediatr Cardiol. 2020 Apr;41(4):772-780
pubmed: 32034462
Med Image Anal. 2022 Aug;80:102484
pubmed: 35649314
Circulation. 2017 Feb 21;135(8):772-785
pubmed: 28034902
Ultrasound Obstet Gynecol. 2020 Dec;56(6):850-856
pubmed: 31875324
Br Heart J. 1979 Mar;41(3):268-74
pubmed: 426975
IEEE Trans Med Imaging. 2021 May;40(5):1438-1449
pubmed: 33544670
Prenat Diagn. 2016 Feb;36(2):127-34
pubmed: 26630206
Med Biol Eng Comput. 2008 Nov;46(11):1097-112
pubmed: 19002516
J Pediatr. 2013 Feb;162(2):302-7.e1
pubmed: 22974576
Sci Rep. 2019 Feb 4;9(1):1130
pubmed: 30718635
Am J Pathol. 1971 May;63(2):203-14
pubmed: 5090637
Front Physiol. 2017 Feb 14;8:68
pubmed: 28261103
Eur Heart J Cardiovasc Imaging. 2023 May 31;24(6):807-818
pubmed: 36441173
Circulation. 2013 Jan 15;127(2):197-206
pubmed: 23224059
Circ Cardiovasc Imaging. 2021 Jul;14(7):e012411
pubmed: 34187165
IEEE Trans Med Imaging. 2009 Aug;28(8):1141-55
pubmed: 19447701
Pediatr Cardiol. 2021 Aug;42(6):1365-1371
pubmed: 33903942
J Clin Med. 2021 Aug 20;10(16):
pubmed: 34441986
Circulation. 2008 Oct 28;118(18):1793-801
pubmed: 18852365
Ultrasound Obstet Gynecol. 2020 Mar;55(3):421-422
pubmed: 31290180
J Ultrasound Med. 2021 Jan;40(1):15-28
pubmed: 32562576
J Thorac Cardiovasc Surg. 2017 Feb;153(2):418-427
pubmed: 27776913
J Pediatr. 2021 Oct;237:102-108.e3
pubmed: 34181988
Am J Cardiol. 1972 Oct;30(5):514-25
pubmed: 4672503
Pediatr Cardiol. 2021 Mar;42(3):517-525
pubmed: 33355680