Perdeuteration of Arenes via Hydrogen Isotope Exchange Catalyzed by the Superbasic Sodium Amide Donor Species NaTMP·PMDETA.
Journal
Journal of the American Chemical Society
ISSN: 1520-5126
Titre abrégé: J Am Chem Soc
Pays: United States
ID NLM: 7503056
Informations de publication
Date de publication:
09 Nov 2022
09 Nov 2022
Historique:
pubmed:
28
10
2022
medline:
28
10
2022
entrez:
27
10
2022
Statut:
ppublish
Résumé
Hydrogen isotope exchange (HIE) has become one of the most studied methods to prepare deuterated molecules, with the primary focus recently on metal-catalyzed C-H activation with transition metals. Here we report the use of a simple sodium amide, NaTMP (TMP = 2,2,6,6-tetramethylpiperidide), combined with tridentate Lewis donor PMDETA (
Identifiants
pubmed: 36302147
doi: 10.1021/jacs.2c09778
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM