Review of prostate cancer genomic studies in Africa.
Africa
GWAS
genomics
omics
prostate cancer
variants
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2022
2022
Historique:
received:
04
04
2022
accepted:
28
09
2022
entrez:
28
10
2022
pubmed:
29
10
2022
medline:
29
10
2022
Statut:
epublish
Résumé
Prostate cancer (PCa) is the second most commonly diagnosed in men worldwide and one of the most frequent cancers in men in Africa. The heterogeneity of this cancer fosters the need to identify potential genetic risk factors/biomarkers. Omics variations may significantly contribute to early diagnosis and personalized treatment. However, there are few genomic studies of this disease in African populations. This review sheds light on the status of genomics research on PCa in Africa and outlines the common variants identified thus far. The allele frequencies of the most significant SNPs in Afro-native, Afro-descendants, and European populations were compared. We advocate how these few but promising data will aid in understanding, better diagnosing, and precisely treating this cancer and the need for further collaborative research on the genomics of PCa in the African continent.
Identifiants
pubmed: 36303548
doi: 10.3389/fgene.2022.911101
pii: 911101
pmc: PMC9593051
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
911101Informations de copyright
Copyright © 2022 Samtal, El Jaddaoui, Hamdi, Bouguenouch, Ouldim, Nejjari, Ghazal and Bekkari.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Science. 2020 Jan 3;367(6473):27-28
pubmed: 31896706
Cold Spring Harb Perspect Med. 2018 Dec 3;8(12):
pubmed: 29311132
PLoS One. 2018 Sep 11;13(9):e0203322
pubmed: 30204798
Curr Opin Genet Dev. 2021 Feb;66:20-24
pubmed: 33373832
EBioMedicine. 2015 Oct 31;2(12):1957-64
pubmed: 26844274
Pac Symp Biocomput. 2016;21:321-32
pubmed: 26776197
Am J Hum Genet. 2017 Jul 6;101(1):5-22
pubmed: 28686856
Asian J Androl. 2013 May;15(3):309-13
pubmed: 23564043
Ann Transl Med. 2016 May;4(10):206
pubmed: 27294245
Pharmacogenomics. 2016 Jul;17(10):1129-1143
pubmed: 27359067
J Proteomics. 2018 Sep 30;188:97-106
pubmed: 28821459
Cell. 2018 Jul 26;174(3):758-769.e9
pubmed: 30033370
N Engl J Med. 2012 Jan 12;366(2):141-9
pubmed: 22236224
Cancer Cell. 2013 Feb 11;23(2):159-70
pubmed: 23410972
Nat Genet. 2009 Oct;41(10):1122-6
pubmed: 19767754
Cancer Epidemiol Biomarkers Prev. 2003 Feb;12(2):120-6
pubmed: 12582021
J Integr Bioinform. 2014 Jun 13;11(2):236
pubmed: 24953305
Nat Commun. 2021 Feb 10;12(1):935
pubmed: 33568675
Genomics. 2019 Jan;111(1):10-16
pubmed: 26902887
Ann Hum Biol. 2018 Sep - Dec;45(6-8):516-523
pubmed: 30616396
World J Oncol. 2019 Apr;10(2):63-89
pubmed: 31068988
Front Oncol. 2020 Dec 14;10:606428
pubmed: 33425763
Am J Transl Res. 2021 Apr 15;13(4):3868-3889
pubmed: 34017579
Br J Cancer. 2004 Jan 26;90(2):510-4
pubmed: 14735201
Cancer Res. 2007 Apr 1;67(7):2951-6
pubmed: 17409400
Prostate. 2010 Feb 15;70(3):270-5
pubmed: 19902474
Int J Biol Markers. 2015 Feb 24;30(1):e148-51
pubmed: 25385241
Cancer Cell. 2010 Jul 13;18(1):11-22
pubmed: 20579941
Annu Rev Genomics Hum Genet. 2008;9:403-33
pubmed: 18593304
PLoS Genet. 2011 May;7(5):e1001387
pubmed: 21637779
Oncotarget. 2018 Nov 30;9(94):36650-36651
pubmed: 30613347
Asian J Androl. 2009 Jan;11(1):49-55
pubmed: 19050691
Hum Genet. 2014 May;133(5):509-21
pubmed: 24185611
Cancer Res. 2018 May 1;78(9):2432-2443
pubmed: 29438991
Eur Urol. 2013 Jul;64(1):173-6
pubmed: 23518396
Eur Urol. 2013 Feb;63(2):347-53
pubmed: 22502944
Nat Genet. 2011 Jun;43(6):570-3
pubmed: 21602798
Cancer Med. 2019 Mar;8(3):1110-1123
pubmed: 30623593
Nat Genet. 2008 Mar;40(3):310-5
pubmed: 18264096
Cancer Res. 2016 Apr 1;76(7):1860-8
pubmed: 26921337
Mol Carcinog. 2002 Jan;33(1):9-15
pubmed: 11807953
J Natl Cancer Inst. 2007 Oct 17;99(20):1525-33
pubmed: 17925536
Cell. 2019 May 2;177(4):1080
pubmed: 31051100
PLoS Genet. 2020 Feb 14;16(2):e1008641
pubmed: 32059012
Am J Clin Pathol. 2012 Jul;138(1):31-41
pubmed: 22706855
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011 Mar;155(1):3-9
pubmed: 21475371
Eur Urol. 2020 Sep;78(3):316-320
pubmed: 32409115
Nat Genet. 2010 Sep;42(9):751-4
pubmed: 20676098
Urol Oncol. 2014 Jan;32(1):53.e15-22
pubmed: 24239470
Clin Cancer Res. 2011 Mar 1;17(5):1075-81
pubmed: 21343373
BMC Med Genomics. 2019 Jun 4;12(1):82
pubmed: 31164124
Cancers (Basel). 2021 Oct 14;13(20):
pubmed: 34680291
Carcinogenesis. 2013 Jun;34(6):1260-4
pubmed: 23393222
Prostate. 2016 Mar;76(4):349-58
pubmed: 26660354
PLoS One. 2016 Apr 13;11(4):e0153496
pubmed: 27073921
Cancer Res. 2018 Dec 15;78(24):6736-6746
pubmed: 30217929
Cancer Epidemiol Biomarkers Prev. 2018 Aug;27(8):845-857
pubmed: 29348298
Int J Mol Sci. 2018 Apr 22;19(4):
pubmed: 29690565
Clin Cancer Res. 2020 Sep 1;26(17):4651-4660
pubmed: 32651179
Nat Genet. 2007 Aug;39(8):977-83
pubmed: 17603485
Nat Genet. 2007 May;39(5):645-9
pubmed: 17401363
Prostate Cancer. 2015;2015:465184
pubmed: 26347821
Cancer Epidemiol Biomarkers Prev. 2011 May;20(5):923-33
pubmed: 21430300
Prostate Cancer. 2013;2013:560857
pubmed: 23476788
Sci Rep. 2015 Aug 10;5:12891
pubmed: 26256549
Prostate. 2014 Dec;74(16):1579-88
pubmed: 25252079
Genome Res. 2016 Feb;26(2):271-7
pubmed: 26627985
Nat Genet. 2008 Mar;40(3):281-3
pubmed: 18264098
Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):811-6
pubmed: 14711987
Prostate. 2012 Sep 1;72(12):1366-73
pubmed: 22234922
Cancer Epidemiol Biomarkers Prev. 2021 Jan;30(1):158-165
pubmed: 33033143
Genes Dev. 2018 Sep 1;32(17-18):1105-1140
pubmed: 30181359
Prostate Cancer. 2011;2011:580318
pubmed: 22191037
Glob Health Action. 2016 May 12;9:31026
pubmed: 27178644
Hum Hered. 2002;54(1):13-21
pubmed: 12446983
Bioinformatics. 2009 Nov 15;25(22):2906-12
pubmed: 19759197
Semin Radiat Oncol. 2017 Jan;27(1):3-10
pubmed: 27986209
Science. 2017 Nov 3;358(6363):652-655
pubmed: 28971970
Int J Cancer. 2017 Feb 15;140(4):788-797
pubmed: 27813082
Nat Genet. 2009 Oct;41(10):1055-7
pubmed: 19767755
Eur Urol. 2018 Mar;73(3):322-339
pubmed: 28927585
Ann Appl Stat. 2013 Mar 1;7(1):523-542
pubmed: 23745156
Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):786-91
pubmed: 20080753
Cell. 2013 Apr 25;153(3):666-77
pubmed: 23622249
Nat Rev Genet. 2018 Mar;19(3):175-185
pubmed: 29151588
Bioinformatics. 2014 May 15;30(10):1370-6
pubmed: 24489367
Nat Rev Cancer. 2021 Jul;21(7):409-410
pubmed: 33846603
Cancer Control. 2022 Jan-Dec;29:10732748221095952
pubmed: 35475404
Endocrine. 2001 Jul;15(2):213-6
pubmed: 11720249
J Hum Genet. 2006;51(2):129-136
pubmed: 16365681
Nature. 2020 Oct;586(7831):741-748
pubmed: 33116287
CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96
pubmed: 18287387
Ecancermedicalscience. 2021 Jun 21;15:1253
pubmed: 34267809
Eur Urol. 2013 Oct;64(4):567-76
pubmed: 23759327
JCO Glob Oncol. 2021 May;7:747-755
pubmed: 34033494
Prostate Cancer Prostatic Dis. 1999 Jan;2(1):9-15
pubmed: 12496860
Biomark Insights. 2017 Mar 16;12:1177271917695810
pubmed: 28469398
Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14068-73
pubmed: 16945910
Genetics. 2002 May;161(1):269-74
pubmed: 12019240
Cancer Res. 2007 Sep 15;67(18):8504-10
pubmed: 17875689
Hum Genet. 2013 Jan;132(1):5-14
pubmed: 23064873
Prostate. 2014 May;74(6):579-89
pubmed: 24783269
Nat Genet. 2008 Mar;40(3):316-21
pubmed: 18264097
Prostate. 2014 Jun;74(8):880-91
pubmed: 24723425
Cancer Epidemiol. 2010 Oct;34(5):598-603
pubmed: 20599479
Cancer Epidemiol. 2011 Oct;35(5):480-4
pubmed: 21193363
Prostate. 2018 Apr;78(5):370-376
pubmed: 29356057
Br J Biomed Sci. 2011;68(3):138-42
pubmed: 21950206
Cancer Epidemiol Biomarkers Prev. 2003 Jul;12(7):604-9
pubmed: 12869398
Oncotarget. 2016 Mar 22;7(12):13945-64
pubmed: 26885621
Cancer Res. 2018 Dec 15;78(24):6726-6727
pubmed: 30552120
Aging Male. 2019 Dec;22(4):219-227
pubmed: 30614347
Prostate Cancer. 2012;2012:798634
pubmed: 23091730
J Transl Med. 2013 May 13;11:121
pubmed: 23668334
Genes (Basel). 2020 Dec 08;11(12):
pubmed: 33302594
Nat Genet. 2018 Jul;50(7):928-936
pubmed: 29892016
Front Genet. 2017 Jun 16;8:84
pubmed: 28670325
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Prostate. 2019 Nov;79(15):1731-1738
pubmed: 31454437
Hum Mol Genet. 2011 Oct 1;20(19):3867-75
pubmed: 21743057
S Afr Med J. 2010 Nov 09;100(11):741-5
pubmed: 21081028
Prostate. 2016 Nov;76(15):1375-86
pubmed: 27418398
Proteomics Clin Appl. 2015 Jun;9(5-6):597-609
pubmed: 25708745
Nat Genet. 2009 Oct;41(10):1116-21
pubmed: 19767753
Genet Test Mol Biomarkers. 2012 Jul;16(7):661-6
pubmed: 22304463
Can J Urol. 2008 Feb;15(1):3872-82
pubmed: 18304397
Cancer Epidemiol Biomarkers Prev. 2011 Jan;20(1):23-32
pubmed: 21071540
Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2525-30
pubmed: 18842992
Front Genet. 2019 Apr 12;10:331
pubmed: 31031807
Pharmacogenomics. 2016 Aug;17(13):1415-23
pubmed: 27471773
Nat Genet. 2006 Jun;38(6):652-8
pubmed: 16682969
Int J Cancer. 2017 Aug 15;141(4):731-743
pubmed: 28510291
PLoS One. 2011 Feb 16;6(2):e16044
pubmed: 21358824
Hum Genet. 2001 Sep;109(3):253-61
pubmed: 11702204
Asian J Urol. 2014 Oct;1(1):15-29
pubmed: 29511634
Nat Genet. 2012 May 20;44(6):685-9
pubmed: 22610119
Front Oncol. 2021 Apr 15;11:650117
pubmed: 33937056