A system suitability testing platform for untargeted, high-resolution mass spectrometry.

analytical chemistry mass spectrometry metabolomics quality assurance quality control

Journal

Frontiers in molecular biosciences
ISSN: 2296-889X
Titre abrégé: Front Mol Biosci
Pays: Switzerland
ID NLM: 101653173

Informations de publication

Date de publication:
2022
Historique:
received: 23 08 2022
accepted: 26 09 2022
entrez: 28 10 2022
pubmed: 29 10 2022
medline: 29 10 2022
Statut: epublish

Résumé

The broad coverage of untargeted metabolomics poses fundamental challenges for the harmonization of measurements along time, even if they originate from the very same instrument. Internal isotopic standards can hardly cover the chemical complexity of study samples. Therefore, they are insufficient for normalizing data

Identifiants

pubmed: 36304928
doi: 10.3389/fmolb.2022.1026184
pii: 1026184
pmc: PMC9592825
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1026184

Informations de copyright

Copyright © 2022 Dmitrenko, Reid and Zamboni.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Andrei Dmitrenko (A)

Institute of Molecular Systems Biology, Department of Biology, ETH Zürich, Zürich, Switzerland.
Life Science Zurich PhD Program on Systems Biology, Zürich, Switzerland.

Michelle Reid (M)

Institute of Molecular Systems Biology, Department of Biology, ETH Zürich, Zürich, Switzerland.

Nicola Zamboni (N)

Institute of Molecular Systems Biology, Department of Biology, ETH Zürich, Zürich, Switzerland.

Classifications MeSH