Child maltreatment, migration and risk of first-episode psychosis: results from the multinational EU-GEI study.
Child adversity
childhood trauma
first-episode psychosis
migrants
Journal
Psychological medicine
ISSN: 1469-8978
Titre abrégé: Psychol Med
Pays: England
ID NLM: 1254142
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
medline:
26
9
2023
pubmed:
29
10
2022
entrez:
28
10
2022
Statut:
ppublish
Résumé
Child maltreatment (CM) and migrant status are independently associated with psychosis. We examined prevalence of CM by migrant status and tested whether migrant status moderated the association between CM and first-episode psychosis (FEP). We further explored whether differences in CM exposure contributed to variations in the incidence rates of FEP by migrant status. We included FEP patients aged 18-64 years in 14 European sites and recruited controls representative of the local populations. Migrant status was operationalized according to generation (first/further) and region of origin (Western/non-Western countries). The reference population was composed by individuals of host country's ethnicity. CM was assessed with Childhood Trauma Questionnaire. Prevalence ratios of CM were estimated using Poisson regression. We examined the moderation effect of migrant status on the odds of FEP by CM fitting adjusted logistic regressions with interaction terms. Finally, we calculated the population attributable fractions (PAFs) for CM by migrant status. We examined 849 FEP cases and 1142 controls. CM prevalence was higher among migrants, their descendants and migrants of non-Western heritage. Migrant status, classified by generation (likelihood test ratio:χ The higher exposure to CM, despite a smaller effect on the odds of FEP, accounted for a greater proportion of incident FEP cases among migrants. Policies aimed at reducing CM should consider the increased vulnerability of specific subpopulations.
Sections du résumé
BACKGROUND
Child maltreatment (CM) and migrant status are independently associated with psychosis. We examined prevalence of CM by migrant status and tested whether migrant status moderated the association between CM and first-episode psychosis (FEP). We further explored whether differences in CM exposure contributed to variations in the incidence rates of FEP by migrant status.
METHODS
We included FEP patients aged 18-64 years in 14 European sites and recruited controls representative of the local populations. Migrant status was operationalized according to generation (first/further) and region of origin (Western/non-Western countries). The reference population was composed by individuals of host country's ethnicity. CM was assessed with Childhood Trauma Questionnaire. Prevalence ratios of CM were estimated using Poisson regression. We examined the moderation effect of migrant status on the odds of FEP by CM fitting adjusted logistic regressions with interaction terms. Finally, we calculated the population attributable fractions (PAFs) for CM by migrant status.
RESULTS
We examined 849 FEP cases and 1142 controls. CM prevalence was higher among migrants, their descendants and migrants of non-Western heritage. Migrant status, classified by generation (likelihood test ratio:χ
CONCLUSIONS
The higher exposure to CM, despite a smaller effect on the odds of FEP, accounted for a greater proportion of incident FEP cases among migrants. Policies aimed at reducing CM should consider the increased vulnerability of specific subpopulations.
Identifiants
pubmed: 36305570
doi: 10.1017/S003329172200335X
pii: S003329172200335X
pmc: PMC10520604
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6150-6160Références
Schizophr Bull. 2022 May 7;48(3):575-589
pubmed: 35137235
J Interpers Violence. 2017 May;32(10):1543-1564
pubmed: 26112971
Psychol Med. 1996 Jul;26(4):775-83
pubmed: 8817712
Psychol Med. 2019 Jun;49(8):1378-1391
pubmed: 30282569
World Psychiatry. 2016 Jun;15(2):93-102
pubmed: 27265690
Int J Psychol. 2013;48(2):117-27
pubmed: 23597011
Br J Psychiatry. 2005 Aug;187:101-2
pubmed: 16055818
Child Abuse Negl. 2003 Feb;27(2):169-90
pubmed: 12615092
Brain Behav Immun. 2021 Jan;91:541-545
pubmed: 33166662
Schizophr Bull. 2011 May;37(3):546-53
pubmed: 19776204
Front Psychiatry. 2020 Mar 09;10:997
pubmed: 32210844
BMC Med Res Methodol. 2003 Oct 20;3:21
pubmed: 14567763
Child Abuse Negl. 2013 Jan;37(1):33-46
pubmed: 23317921
Schizophr Res Cogn. 2020 Oct 23;23:100189
pubmed: 33134093
Schizophr Bull. 2012 Jun;38(4):661-71
pubmed: 22461484
Int J Public Health. 2019 Mar;64(2):241-251
pubmed: 30506365
Int J Psychol. 2013;48(2):95-107
pubmed: 23597009
Health Aff (Millwood). 2005 Mar-Apr;24(2):343-52
pubmed: 15757918
Soc Psychiatry Psychiatr Epidemiol. 2020 May;55(5):645-657
pubmed: 31974809
Child Maltreat. 2011 Feb;16(1):63-73
pubmed: 21041234
BMJ Open. 2013 Aug 01;3(8):
pubmed: 23906948
Schizophr Bull. 2012 Jun;38(4):672-5
pubmed: 22837349
Psychol Bull. 1993 Jan;113(1):82-98
pubmed: 8426875
Psychol Med. 2021 Mar 02;:1-9
pubmed: 33648622
J Affect Disord. 2019 Sep 1;256:448-457
pubmed: 31252238
Neuroimage. 2014 Aug 15;97:236-44
pubmed: 24736182
Psychol Med. 2021 Jul;51(9):1536-1548
pubmed: 32122439
Bioinformatics. 2012 Jan 1;28(1):112-8
pubmed: 22039212
Int J Epidemiol. 2014 Jun;43(3):962-70
pubmed: 24603316
BMC Public Health. 2018 Oct 10;18(1):1164
pubmed: 30305071
BMC Psychiatry. 2019 Dec 27;19(1):418
pubmed: 31882002
World Psychiatry. 2021 Oct;20(3):417-436
pubmed: 34505386
Int J Epidemiol. 2018 Jun 1;47(3):780-787
pubmed: 29390062
Psychol Med. 2022 Oct;52(14):2972-2984
pubmed: 33563347
Psychol Med. 2000 May;30(3):529-44
pubmed: 10883709
BMC Med Res Methodol. 2008 Dec 16;8:80
pubmed: 19087281
Psychol Med. 2020 Jan;50(2):303-313
pubmed: 30722795
Br J Psychiatry. 2020 Oct;217(4):575-582
pubmed: 32778182
Annu Rev Public Health. 2008;29:235-52
pubmed: 18031225
Child Abuse Negl. 2015 Mar;41:30-9
pubmed: 25169149
Am J Med. 1999 Oct;107(4):332-9
pubmed: 10527034
Healthcare (Basel). 2021 Aug 30;9(9):
pubmed: 34574904
Child Abuse Negl. 2020 May;103:104439
pubmed: 32126398
Psychol Med. 2023 Apr;53(5):1970-1978
pubmed: 37310339
Lancet. 2005 Apr 9-15;365(9467):1309-14
pubmed: 15823380
Psychol Med. 2022 May;52(7):1376-1385
pubmed: 32958094
Am J Public Health. 2010 Apr 1;100 Suppl 1:S186-96
pubmed: 20147693
Lancet Psychiatry. 2019 May;6(5):427-436
pubmed: 30902669
World Psychiatry. 2019 Oct;18(3):247-258
pubmed: 31496097
Mol Psychiatry. 2022 Aug;27(8):3510-3519
pubmed: 35484237
Br J Psychiatry. 2009 Dec;195(6):488-91
pubmed: 19949195