Five-Year Symptom Trajectories in Nondialysis-Dependent CKD Patients.
CKD
clinical epidemiology
cohort studies
quality of life
symptoms
Journal
Clinical journal of the American Society of Nephrology : CJASN
ISSN: 1555-905X
Titre abrégé: Clin J Am Soc Nephrol
Pays: United States
ID NLM: 101271570
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
received:
23
05
2022
accepted:
19
09
2022
pubmed:
29
10
2022
medline:
10
11
2022
entrez:
28
10
2022
Statut:
ppublish
Résumé
Late stages of CKD are characterized by significant symptom burden. This study aimed to identify subgroups within the 5-year trajectories of symptom evolution in patients with CKD and to describe associated patient characteristics and outcomes. Among 2787 participants (66% men) with eGFR <60 ml/min per 1.73 m Patient mean age (±SD) at baseline was 67±13 years, and mean eGFR was 33±13 ml/min per 1.73 m This study highlights a significant worsening of symptoms in about one third of the participants, whereas the majority reported low symptom severity throughout the study.
Sections du résumé
BACKGROUND AND OBJECTIVES
Late stages of CKD are characterized by significant symptom burden. This study aimed to identify subgroups within the 5-year trajectories of symptom evolution in patients with CKD and to describe associated patient characteristics and outcomes.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS
Among 2787 participants (66% men) with eGFR <60 ml/min per 1.73 m
RESULTS
Patient mean age (±SD) at baseline was 67±13 years, and mean eGFR was 33±13 ml/min per 1.73 m
CONCLUSIONS
This study highlights a significant worsening of symptoms in about one third of the participants, whereas the majority reported low symptom severity throughout the study.
Identifiants
pubmed: 36307136
pii: 01277230-202211000-00006
doi: 10.2215/CJN.06140522
pmc: PMC9718050
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1588-1597Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2022 by the American Society of Nephrology.
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