Animal models of alphavirus infection and human disease.

Animals Humans Alphavirus Infections / pathology Alphavirus / genetics Disease Models, Animal
Alphavirus Animal model Arthritogenic Encephalitic Pathogenesis

Journal

Advances in virus research
ISSN: 1557-8399
Titre abrégé: Adv Virus Res
Pays: United States
ID NLM: 0370441

Informations de publication

Date de publication:
2022
Historique:
entrez: 28 10 2022
pubmed: 29 10 2022
medline: 2 11 2022
Statut: ppublish

Résumé

Alphaviruses are a large group (>30 species) of enveloped, positive-strand RNA viruses. The re-emergence of mosquito-transmitted alphaviruses associated with human diseases ranging from severe and potentially fatal neurological disease to chronic arthritic disease highlights the need to understand the biology and pathogenesis of alphaviruses. Here, we review the development and use of animal models of alphavirus transmission and human disease, and discuss areas for continued refinement of these models including possible avenues for future investigation.

Identifiants

DOI: 10.1016/bs.aivir.2022.07.001 PMID: 36307168
pubmed: 36307168
pii: S0065-3527(22)00019-7
doi: 10.1016/bs.aivir.2022.07.001
pii:
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

25-88

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Cormac J Lucas (CJ)

Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States; RNA Bioscience Initiative, University of Colorado School of Medicine, Aurora, CO, United States.

Thomas E Morrison (TE)

Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States. Electronic address: thomas.morrison@cuanschutz.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Animal models of alphavirus infection and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Animal models of alphavirus infection and...
questionsmedicales.fr › Infection › Maladies virales › Infections à virus à ARN › Infections à Togaviridae › Infections à alphavirus › Animal models of alphavirus infection and...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Togaviridae › Alphavirus › Animal models of alphavirus infection and...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Animal models of alphavirus infection and...