Role of brain 2-[
2-[18F]FDG-PET
Amyotrophic lateral sclerosis
Prediction model
Survival
Journal
European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
16
06
2022
accepted:
29
09
2022
pubmed:
30
10
2022
medline:
24
1
2023
entrez:
29
10
2022
Statut:
ppublish
Résumé
The identification of prognostic tools in amyotrophic lateral sclerosis (ALS) would improve the design of clinical trials, the management of patients, and life planning. We aimed to evaluate the accuracy of brain 2-[ A prospective cohort study enrolled 418 ALS patients, who underwent brain 2-[ Data were discretized in three survival profiles: 0-2 years, 2-5 years, and > 5 years. SVM resulted in an error rate < 20% for two out of three classes separately. As for class one, the discriminant clusters included left caudate body and anterior cingulate cortex. The most discriminant regions were bilateral cerebellar pyramid in class two, and right cerebellar dentate nucleus, and left cerebellar nodule in class three. Brain 2-[
Identifiants
pubmed: 36308536
doi: 10.1007/s00259-022-05987-3
pii: 10.1007/s00259-022-05987-3
pmc: PMC9852209
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
784-791Informations de copyright
© 2022. The Author(s).
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