Improving adult pulsatile minimal invasive extracorporeal circulation in a mock circulation.
cannula
diagonal pump
minimal invasive extracorporeal circulation
oxygenator
pulsatile perfusion
surplus hemodynamic energy
Journal
Artificial organs
ISSN: 1525-1594
Titre abrégé: Artif Organs
Pays: United States
ID NLM: 7802778
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
revised:
05
08
2022
received:
27
05
2022
accepted:
11
10
2022
medline:
15
5
2023
pubmed:
1
11
2022
entrez:
31
10
2022
Statut:
ppublish
Résumé
Pulsatile extracorporeal circulation (ECC) may improve perfusion of critical organs during cardiac surgery. This study analyzed the influence of the components of a minimal invasive ECC (MiECC) on the transfer of pulsatile energy into the pseudo-patient of a mock circulation. An aortic model with human-like geometry and compliance was perfused by a diagonal pump. Surplus hemodynamic energy (SHE) was determined from flow and pressure data. Five adult-size oxygenator models and three sizes of cannulas were compared. Pulsatile pump settings were optimized, and parallel dual-pump configurations were evaluated. Oxygenator models showed up to twofold differences in pressure gradients and influenced SHE at flow rates up to 2.0 L min Proper selection of components and optimizations of pump settings significantly improved pulse pressure and SHE of pulsatile MiECC. Surplus hemodynamic energy depended on flow rate with a maximum at 1.0 L min
Sections du résumé
BACKGROUND
BACKGROUND
Pulsatile extracorporeal circulation (ECC) may improve perfusion of critical organs during cardiac surgery. This study analyzed the influence of the components of a minimal invasive ECC (MiECC) on the transfer of pulsatile energy into the pseudo-patient of a mock circulation.
METHODS
METHODS
An aortic model with human-like geometry and compliance was perfused by a diagonal pump. Surplus hemodynamic energy (SHE) was determined from flow and pressure data. Five adult-size oxygenator models and three sizes of cannulas were compared. Pulsatile pump settings were optimized, and parallel dual-pump configurations were evaluated.
RESULTS
RESULTS
Oxygenator models showed up to twofold differences in pressure gradients and influenced SHE at flow rates up to 2.0 L min
CONCLUSIONS
CONCLUSIONS
Proper selection of components and optimizations of pump settings significantly improved pulse pressure and SHE of pulsatile MiECC. Surplus hemodynamic energy depended on flow rate with a maximum at 1.0 L min
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
828-839Informations de copyright
© 2022 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.
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