Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome.
Autism
Cognitive ability
Down syndrome
Females
Sex-differences
Journal
Journal of autism and developmental disorders
ISSN: 1573-3432
Titre abrégé: J Autism Dev Disord
Pays: United States
ID NLM: 7904301
Informations de publication
Date de publication:
31 Oct 2022
31 Oct 2022
Historique:
accepted:
28
09
2022
pmc-release:
30
04
2024
entrez:
31
10
2022
pubmed:
1
11
2022
medline:
1
11
2022
Statut:
aheadofprint
Résumé
This study explores sex-differences in (a) rates and profiles of autism symptoms as well as in (b) the contribution of intellectual quotient (IQ) to autism symptom presentation in Down syndrome (DS). Participants were 40 males and 38 females with DS, aged 6 to 23 years. Autism symptoms were rated through the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2). Results show no sex differences in the ADOS-2 Calibrated Severity Scores (CSS). However, only females with DS who are classified as DS-Only have higher scores on verbal IQ than those classified as DS + autism. Furthermore, associations between IQ and all CSSs are found for females, but not for males. Findings suggest that verbal cognition may play differential roles for females and males with DS.
Identifiants
pubmed: 36315322
doi: 10.1007/s10803-022-05779-6
pii: 10.1007/s10803-022-05779-6
pmc: PMC10184887
mid: NIHMS1895176
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NICHD NIH HHS
ID : R01 HD074346
Pays : United States
Organisme : NIMH NIH HHS
ID : T32 MH073124
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1TR001860
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001860
Pays : United States
Organisme : NICHD NIH HHS
ID : P50 HD103526
Pays : United States
Informations de copyright
© 2022. The Author(s).
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