Impact of host age on viral and bacterial communities in a waterbird population.
Journal
The ISME journal
ISSN: 1751-7370
Titre abrégé: ISME J
Pays: England
ID NLM: 101301086
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
22
03
2022
accepted:
11
10
2022
revised:
03
10
2022
pubmed:
3
11
2022
medline:
25
1
2023
entrez:
2
11
2022
Statut:
ppublish
Résumé
Wildlife harbour pathogens that can harm human or livestock health and are the source of most emerging infectious diseases. It is rarely considered how changes in wildlife population age-structures or how age-stratified behaviours might alter the level of pathogen detection within a species, or risk of spillover to other species. Micro-organisms that occur in healthy animals can be an important model for understanding and predicting the dynamics of pathogens of greater health concern, which are hard to study in wild populations due to their relative rarity. We therefore used a metagenomic approach to jointly characterise viral and prokaryotic carriage in faeces collected from a healthy wild bird population (Cygnus olor; mute swan) that has been subject to long-term study. Using 223 samples from known individuals allowed us to compare differences in prokaryotic and eukaryotic viral carriage between adults and juveniles at an unprecedented level of detail. We discovered and characterised 77 novel virus species, of which 21% belong putatively to bird-infecting families, and described the core prokaryotic microbiome of C. olor. Whilst no difference in microbiota diversity was observed between juveniles and adult individuals, 50% (4/8) of bird-infecting virus families (picornaviruses, astroviruses, adenoviruses and bornaviruses) and 3.4% (9/267) of prokaryotic families (including Helicobacteraceae, Spirochaetaceae and Flavobacteriaceae families) were differentially abundant and/or prevalent between juveniles and adults. This indicates that perturbations that affect population age-structures of wildlife could alter circulation dynamics and spillover risk of microbes, potentially including pathogens.
Identifiants
pubmed: 36319706
doi: 10.1038/s41396-022-01334-4
pii: 10.1038/s41396-022-01334-4
pmc: PMC9860062
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
215-226Subventions
Organisme : Wellcome Trust
ID : 220414/Z/20/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 102427/Z/13/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 090532/Z/09/Z
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/T008806/1
Pays : United Kingdom
Informations de copyright
© 2022. The Author(s).
Références
Proc Biol Sci. 2021 May 26;288(1951):20210480
pubmed: 34034514
Mov Ecol. 2020 Feb 07;8:7
pubmed: 32047635
Bioinformatics. 2014 May 1;30(9):1312-3
pubmed: 24451623
Emerg Infect Dis. 2005 Dec;11(12):1842-7
pubmed: 16485468
Int J Environ Res Public Health. 2020 Mar 18;17(6):
pubmed: 32197367
J Anim Ecol. 2014 Jan;83(1):266-75
pubmed: 24033258
Bioinformatics. 2011 Apr 15;27(8):1164-5
pubmed: 21335321
PLoS One. 2014 Apr 02;9(4):e93269
pubmed: 24695106
Elife. 2020 Jul 28;9:
pubmed: 32718436
Appl Environ Microbiol. 2016 May 31;82(12):3537-3545
pubmed: 27060114
Front Microbiol. 2015 Jul 03;6:673
pubmed: 26191057
Arch Gesamte Virusforsch. 1973;40(1):52-7
pubmed: 4632560
J Gen Virol. 2020 Aug;101(8):785-790
pubmed: 32519942
PLoS One. 2016 Apr 26;11(4):e0154338
pubmed: 27115881
Mov Ecol. 2015 Aug 15;3(1):19
pubmed: 26279850
Nucleic Acids Res. 2002 Jul 15;30(14):3059-66
pubmed: 12136088
Philos Trans R Soc Lond B Biol Sci. 2001 Jul 29;356(1411):991-9
pubmed: 11516377
Mol Biol Evol. 2013 Apr;30(4):772-80
pubmed: 23329690
Curr Protoc Bioinformatics. 2010 Dec;Chapter 11:Unit 11.7
pubmed: 21154709
PLoS Pathog. 2017 Jan 31;13(1):e1006198
pubmed: 28141833
Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6587-92
pubmed: 16618935
J Virol. 2019 May 15;93(11):
pubmed: 30867308
Front Microbiol. 2014 May 16;5:223
pubmed: 24904538
Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10208-13
pubmed: 21646516
Nucleic Acids Res. 2005 Apr 07;33(6):e65
pubmed: 15817564
Ecol Evol. 2017 Jun 15;7(15):5732-5745
pubmed: 28808547
J Gen Virol. 2019 Mar;100(3):367-368
pubmed: 30672729
Virology. 2021 Sep;561:98-106
pubmed: 34182259
PLoS One. 2014 Sep 26;9(9):e108277
pubmed: 25259891
J Virol. 2010 Oct;84(19):10322-8
pubmed: 20668077
Am J Primatol. 2015 Jan;77(1):98-108
pubmed: 25219793
Avian Dis. 2012 Mar;56(1):153-9
pubmed: 22545541
Genome Res. 2008 May;18(5):821-9
pubmed: 18349386
J Gen Virol. 2017 Oct;98(10):2421-2422
pubmed: 28884666
Genome Biol. 2014 Mar 03;15(3):R46
pubmed: 24580807
Proc Biol Sci. 2016 Dec 28;283(1845):
pubmed: 28003449
Bioinformatics. 2012 Jun 15;28(12):1647-9
pubmed: 22543367
Proc Biol Sci. 2002 Apr 7;269(1492):671-6
pubmed: 11934357
Curr Opin Virol. 2018 Feb;28:26-36
pubmed: 29121508
Science. 2011 Jan 21;331(6015):296-302
pubmed: 21252339
mSystems. 2019 Jun 25;4(4):
pubmed: 31239396
Influenza Other Respir Viruses. 2008 Sep;2(5):155-63
pubmed: 19453420
FEMS Microbiol Lett. 2014 Nov;360(2):100-12
pubmed: 25263745
Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11488-93
pubmed: 21709237
J Clin Microbiol. 1990 Mar;28(3):495-503
pubmed: 1691208
Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7374-7379
pubmed: 29941567
Sci Data. 2016 Mar 01;3:160006
pubmed: 26928014
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8399-404
pubmed: 23671097
Nucleic Acids Res. 2014 Jan;42(Database issue):D633-42
pubmed: 24288368
Nat Methods. 2015 Jan;12(1):59-60
pubmed: 25402007
J Anim Ecol. 2020 Jul;89(7):1549-1558
pubmed: 32248522
Emerg Infect Dis. 2012 Feb;18(2):234-41
pubmed: 22304809
BMC Ecol. 2013 Mar 25;13:11
pubmed: 23531085
Philos Trans R Soc Lond B Biol Sci. 2019 Jun 24;374(1775):20180259
pubmed: 31056057
Ecol Lett. 2018 Apr;21(4):471-483
pubmed: 29466832
PLoS One. 2012;7(6):e39692
pubmed: 22761872
Philos Trans R Soc Lond B Biol Sci. 2020 Nov 9;375(1811):20190613
pubmed: 32951554
J Mol Biol. 1990 Oct 5;215(3):403-10
pubmed: 2231712
Vet Microbiol. 2014 Aug 6;172(1-2):146-56
pubmed: 24933163
Nat Commun. 2017 Oct 24;8(1):1124
pubmed: 29066781
Nucleic Acids Res. 2004 Mar 19;32(5):1792-7
pubmed: 15034147