A manifesto on explainability for artificial intelligence in medicine.

Artificial intelligence Explainability Explainable artificial intelligence Interpretability Interpretable artificial intelligence

Journal

Artificial intelligence in medicine
ISSN: 1873-2860
Titre abrégé: Artif Intell Med
Pays: Netherlands
ID NLM: 8915031

Informations de publication

Date de publication:
11 2022
Historique:
received: 02 03 2022
revised: 04 10 2022
accepted: 04 10 2022
entrez: 3 11 2022
pubmed: 4 11 2022
medline: 8 11 2022
Statut: ppublish

Résumé

The rapid increase of interest in, and use of, artificial intelligence (AI) in computer applications has raised a parallel concern about its ability (or lack thereof) to provide understandable, or explainable, output to users. This concern is especially legitimate in biomedical contexts, where patient safety is of paramount importance. This position paper brings together seven researchers working in the field with different roles and perspectives, to explore in depth the concept of explainable AI, or XAI, offering a functional definition and conceptual framework or model that can be used when considering XAI. This is followed by a series of desiderata for attaining explainability in AI, each of which touches upon a key domain in biomedicine.

Identifiants

pubmed: 36328669
pii: S0933-3657(22)00175-0
doi: 10.1016/j.artmed.2022.102423
pii:
doi:

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

102423

Subventions

Organisme : NCATS NIH HHS
ID : UL1 TR001878
Pays : United States

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Carlo Combi (C)

University of Verona, Verona, Italy. Electronic address: carlo.combi@univr.it.

Beatrice Amico (B)

University of Verona, Verona, Italy.

Riccardo Bellazzi (R)

University of Pavia, Pavia, Italy.

Andreas Holzinger (A)

Medical University Graz, Graz, Austria.

Jason H Moore (JH)

Cedars-Sinai Medical Center, West Hollywood, CA, USA.

Marinka Zitnik (M)

Harvard Medical School and Broad Institute of MIT & Harvard, MA, USA.

John H Holmes (JH)

University of Pennsylvania Perelman School of Medicine Philadelphia, PA, USA.

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Classifications MeSH