Refraction development in anisometropic amblyopia with patching therapy.
amblyopia
anisometropia
anisometropic amblyopia
emmetropization
myopic shift
patching therapy
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2022
2022
Historique:
received:
01
06
2022
accepted:
26
09
2022
entrez:
4
11
2022
pubmed:
5
11
2022
medline:
5
11
2022
Statut:
epublish
Résumé
To investigate the development of refraction in anisometropic amblyopia who had been with patching therapy. We retrospectively reviewed 37,528 medical records of the amblyopes who had been treated with patching therapy between July 2003 and January 2020 at the School of Optometry and Ophthalmology and Eye Hospital of Wenzhou Medical University. We included unilateral anisometropic amblyopia with a follow-up length of not < 2 years. In total, 371 cases were enrolled and followed up for a mean of 4.76 ± 2.11 years. The subjects were then divided into different groups and periods according to their initial spherical equivalent (SE) refractive error and best-corrected visual acuity (BCVA) of the amblyopic eye. Linear mixed-effects models were fitted to calculate the annual change of SE. The annual changes in SE were -0.32 (-0.35 to -0.30) and -0.16 (-0.19 to -0.14) D/yr for the amblyopic eye and the fellow eye, respectively. The annual changes in SE of amblyopic eyes during the treatment period and the successfully treated period were -0.36 (-0.43 to -0.29; 95% CI) and -0.27 (-0.32 to -0.23; 95% CI) D/yr, respectively; the annual SE changes of the fellow eye during the treatment period and the successfully-treated period were -0.07 (-0.14 to -0.01; 95% CI) and -0.18 (-0.22 to -0.14; 95% CI) D/yr, respectively. The amblyopic eye experienced a significantly greater degree of refractive error changes than the fellow eye and underwent a continuous refractive error reduction before and after 7 years old. After the patching therapy was terminated, emmetropization in the amblyopic eye remained synchronized, whereas the refractive error change was increased in the fellow eye.
Identifiants
pubmed: 36330057
doi: 10.3389/fmed.2022.959085
pmc: PMC9623012
doi:
Types de publication
Journal Article
Langues
eng
Pagination
959085Informations de copyright
Copyright © 2022 Chen, Zuo, Xiong, Yu, Wei, Luo, Bao, Chen and Zhou.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Ophthalmology. 2018 Jan;125(1):P105-P142
pubmed: 29108744
Invest Ophthalmol Vis Sci. 1981 Apr;20(4):561-4
pubmed: 7216673
Vision Res. 1995 May;35(9):1325-8
pubmed: 7610593
Br J Ophthalmol. 2020 Sep;104(9):1283-1287
pubmed: 31806647
Ophthalmology. 2010 Nov;117(11):2196-207.e1
pubmed: 20580093
Br J Ophthalmol. 1984 Feb;68(2):105-12
pubmed: 6691952
JAMA Ophthalmol. 2014 Jul;132(7):799-805
pubmed: 24789375
Vision Res. 2020 Nov;176:118-129
pubmed: 32866759
Eye (Lond). 1992;6 ( Pt 2):154-60
pubmed: 1624037
Medicina (Kaunas). 2018 Mar 20;54(1):
pubmed: 30344237
Ophthalmic Physiol Opt. 1999 Mar;19(2):90-102
pubmed: 10615445
Ophthalmology. 2021 Nov;128(11):1652-1654
pubmed: 33857574
Surv Ophthalmol. 1995 Nov-Dec;40(3):207-16
pubmed: 8599156
JAMA Ophthalmol. 2021 Mar 1;139(3):293-300
pubmed: 33443542
Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1779-1800
pubmed: 28346616
Nutr Clin Pract. 2021 Jun;36(3):598-605
pubmed: 33956359
Curr Opin Ophthalmol. 1999 Oct;10(5):293-9
pubmed: 10621540
Arch Ophthalmol. 2002 Mar;120(3):281-7
pubmed: 11879130
Optom Vis Sci. 2015 Oct;92(10):1012-5
pubmed: 26258279
J Binocul Vis Ocul Motil. 2019 Jul-Sep;69(3):116-125
pubmed: 31161888
Vision Res. 2006 Jan;46(1-2):267-83
pubmed: 16139323
Am J Ophthalmol. 1975 Sep;80(3 Pt 2):485-90
pubmed: 1163595
Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):3127-3134
pubmed: 31323683
Strabismus. 2009 Jan-Mar;17(1):16-9
pubmed: 19301187
Br J Ophthalmol. 1996 Oct;80(10):860-3
pubmed: 8976694
Vision Res. 2011 Jan;51(1):48-57
pubmed: 20932989
Ophthalmic Physiol Opt. 1991 Oct;11(4):297-303
pubmed: 1771066
Ophthalmic Physiol Opt. 2014 Mar;34(2):146-62
pubmed: 24588532
Lancet. 2006 Apr 22;367(9519):1343-51
pubmed: 16631913
Optom Vis Sci. 1993 Dec;70(12):1019-26
pubmed: 8115124
Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):6
pubmed: 34989762
iScience. 2021 Jun 12;24(7):102727
pubmed: 34258558
Br J Ophthalmol. 2013 Sep;97(9):1095-9
pubmed: 23613508
BMJ. 2015 Nov 12;351:h5811
pubmed: 26563241
Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2203-12
pubmed: 27116548
Eye (Lond). 2014 Feb;28(2):169-79
pubmed: 24406411
Ophthalmology. 2009 Nov;116(11):2128-34.e1-2
pubmed: 19762084
Arch Ophthalmol. 2001 Nov;119(11):1625-8
pubmed: 11709012
Br J Ophthalmol. 2020 Aug;104(8):1164-1170
pubmed: 31704700
Ophthalmology. 2011 Aug;118(8):1495-500
pubmed: 21529955
Vision Res. 2017 May;134:26-42
pubmed: 28404522
Ophthalmic Physiol Opt. 1991 Oct;11(4):350-8
pubmed: 1771072
Curr Opin Ophthalmol. 2002 Oct;13(5):337-40
pubmed: 12218466
Doc Ophthalmol. 1984 Jan 30;56(3):265-74
pubmed: 6705671
Vis Neurosci. 2018 Jan;35:E014
pubmed: 29905116