The impact of antigenic molecular mimicry on anti-cancer T-cell immune response.

anti-cancer immune response cancer vaccine cross-reacting T cells microbiota molecular mimicry tumor antigen virus

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2022
Historique:
received: 01 08 2022
accepted: 29 09 2022
entrez: 4 11 2022
pubmed: 5 11 2022
medline: 5 11 2022
Statut: epublish

Résumé

Individuals are exposed to intracellular pathogens (i.e. viruses and intracellular bacteria) and intestinal microbiota, collectively microorganisms (MOs), which enter the body during the host's lifetime. Altogether, MOs are a natural source of non-self antigens (MoAs) expressed by host's cells in the context of the HLA class I molecules, inducing a wide pool of specific memory CD8

Identifiants

pubmed: 36330482
doi: 10.3389/fonc.2022.1009247
pmc: PMC9623278
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1009247

Informations de copyright

Copyright © 2022 Tagliamonte and Buonaguro.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Maria Tagliamonte (M)

Innovative Immunological Models Unit, Istituto Nazionale Tumori - IRCCS - "Fond G. Pascale", Naples, Italy.

Luigi Buonaguro (L)

Innovative Immunological Models Unit, Istituto Nazionale Tumori - IRCCS - "Fond G. Pascale", Naples, Italy.

Classifications MeSH