Acinic cell carcinoma of the breast: A comprehensive review.
Acinic cell carcinoma
Breast cancer
Salivary gland-type tumors
Special types
Journal
Breast (Edinburgh, Scotland)
ISSN: 1532-3080
Titre abrégé: Breast
Pays: Netherlands
ID NLM: 9213011
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
25
06
2022
revised:
03
10
2022
accepted:
19
10
2022
pubmed:
5
11
2022
medline:
27
12
2022
entrez:
4
11
2022
Statut:
ppublish
Résumé
Acinic cell carcinoma of the breast is a rare special subtype of breast cancer in the category of salivary gland-type tumors. It is morphologically similar to acinic cell carcinomas of salivary glands and pancreas and has a triple-negative phenotype (estrogen receptor-negative, progesterone receptor-negative, and Her-2/neu negative). Its molecular genomic features are more similar to triple-negative breast cancer of no special type than to its salivary gland counterpart. However, the clinical course of the mammary acinic cell carcinoma appears to be less aggressive than the usual triple-negative breast carcinomas. This review comprehensively summarizes the current literature on the clinicopathologic, immunohistochemical, and molecular features of this rare and distinct subtype of breast cancer.
Identifiants
pubmed: 36332545
pii: S0960-9776(22)00177-1
doi: 10.1016/j.breast.2022.10.012
pmc: PMC9636467
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
208-216Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare no conflict of interest.