Leishmaniasis.
Allopurinol
Canine leishmaniasis
Co-infection
Feline leishmaniasis
Leishmania infantum
Meglumine antimoniate
Miltefosine
Topical insecticides
Journal
The Veterinary clinics of North America. Small animal practice
ISSN: 1878-1306
Titre abrégé: Vet Clin North Am Small Anim Pract
Pays: United States
ID NLM: 7809942
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
entrez:
6
11
2022
pubmed:
7
11
2022
medline:
9
11
2022
Statut:
ppublish
Résumé
Leishmaniasis caused by Leishmania infantum is an important zoonotic disease transmitted by sand flies with a high prevalence of infection in dogs and cats in regions whereby transmission occurs. Clinical disease is systemic with variable presenting signs and degrees of severity. It affects the skin, lymph nodes, eyes, bone marrow, kidneys, and other organs. The clinical findings in dogs and cats with L. infantum infection are generally similar. Subclinical infection of canines and felines in endemic areas is frequent. Long-term treatment of the disease with allopurinol, or combination of allopurinol with meglumine antimoniate or miltefosine, is needed, and clinical relapse is probable.
Identifiants
pubmed: 36336425
pii: S0195-5616(22)00087-0
doi: 10.1016/j.cvsm.2022.06.012
pii:
doi:
Substances chimiques
Allopurinol
63CZ7GJN5I
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1359-1375Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure The authors declare that they have no conflict of interest related to any of the topics presented in this publication.