Radiological Features of Bilateral Sequential Leukaemic Optic Nerve Infiltration: A Case Report.
Leukaemia
MRI
optic nerve infiltration
Journal
Neuro-ophthalmology (Aeolus Press)
ISSN: 0165-8107
Titre abrégé: Neuroophthalmology
Pays: England
ID NLM: 8408966
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
7
11
2022
pubmed:
8
11
2022
medline:
8
11
2022
Statut:
epublish
Résumé
Leukaemic infiltration of the optic nerve is an oncologic emergency that can lead to a significant risk of irreversible vision loss and has an overall poor systemic prognosis. We present the case of a 77-year-old man in previous systemic remission from acute myeloid leukaemia (AML) who developed bilateral sequential leukaemic optic nerve involvement with eventual complete vision loss. A review of the clinical and radiological characteristics of optic nerve infiltration in AML is provided. Profound vision loss to the order of 20/200 or worse is common. Magnetic resonance imaging features include optic nerve thickening, enhancement of the nerve sheath, T2 hyperintensity and restricted diffusion. Urgent orbital radiotherapy is indicated prior to the onset of irreversible optic nerve damage.
Identifiants
pubmed: 36337226
doi: 10.1080/01658107.2022.2041047
pii: 2041047
pmc: PMC9635559
doi:
Types de publication
Case Reports
Langues
eng
Pagination
322-326Informations de copyright
© 2022 Taylor & Francis Group, LLC.
Déclaration de conflit d'intérêts
No potential conflict of interest was reported by the authors.
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