bHLH heterodimer complex variations regulate cell proliferation activity in the meristems of

Biological sciences Molecular plant pathology Natural sciences Plant biology

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
18 Nov 2022
Historique:
received: 15 10 2021
revised: 08 08 2022
accepted: 12 10 2022
entrez: 7 11 2022
pubmed: 8 11 2022
medline: 8 11 2022
Statut: epublish

Résumé

Root, shoot, and lateral meristems are the main regions of cell proliferation in plants. It has been proposed that meristems might have evolved dedicated transcriptional networks to balance cell proliferation. Here, we show that basic helix-loop-helix (bHLH) transcription factor heterodimers formed by members of the TARGET OF MONOPTEROS5 (TMO5) and LONESOME HIGHWAY (LHW) subclades are general regulators of cell proliferation in all meristems. Yet, genetics and expression analyses suggest specific functions of these transcription factors in distinct meristems, possibly due to their expression domains determining heterodimer complex variations within meristems, and to a certain extent to the absence of some of them in a given meristem. Target gene specificity analysis for heterodimer complexes focusing on the

Identifiants

pubmed: 36339262
doi: 10.1016/j.isci.2022.105364
pii: S2589-0042(22)01636-4
pmc: PMC9626673
doi:

Types de publication

Journal Article

Langues

eng

Pagination

105364

Informations de copyright

© 2022 The Authors.

Déclaration de conflit d'intérêts

The authors declare no competing interests.

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Auteurs

Eliana Mor (E)

Ghent University, Department of Plant Biotechnology and Bioinformatics, Technologiepark 71, 9052 Ghent, Belgium.
VIB Centre for Plant Systems Biology, Technologiepark 71, 9052 Ghent, Belgium.

Markéta Pernisová (M)

Laboratoire Reproduction et Développement des Plantes, University Lyon, ENS de Lyon, CNRS, INRAE, INRIA, 69342 Lyon, France.
Functional Genomics and Proteomics, National Centre for Biomolecular Research, Faculty of Science, and Plant Sciences Core Facility, Mendel Centre for Plant Genomics and Proteomics, Central European Institute of Technology (CEITEC), Masaryk University, 62500 Brno, Czechia.
Institute of Synthetic Biology and CEPLAS, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

Max Minne (M)

Ghent University, Department of Plant Biotechnology and Bioinformatics, Technologiepark 71, 9052 Ghent, Belgium.
VIB Centre for Plant Systems Biology, Technologiepark 71, 9052 Ghent, Belgium.

Guillaume Cerutti (G)

Laboratoire Reproduction et Développement des Plantes, University Lyon, ENS de Lyon, CNRS, INRAE, INRIA, 69342 Lyon, France.

Dagmar Ripper (D)

ZMBP-Center for Plant Molecular Biology, University of Tübingen, Auf der Morgenstelle 32, 72076 Tübingen, Germany.

Jonah Nolf (J)

Ghent University, Department of Plant Biotechnology and Bioinformatics, Technologiepark 71, 9052 Ghent, Belgium.
VIB Centre for Plant Systems Biology, Technologiepark 71, 9052 Ghent, Belgium.

Jennifer Andres (J)

Institute of Synthetic Biology and CEPLAS, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

Laura Ragni (L)

ZMBP-Center for Plant Molecular Biology, University of Tübingen, Auf der Morgenstelle 32, 72076 Tübingen, Germany.

Matias D Zurbriggen (MD)

Institute of Synthetic Biology and CEPLAS, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

Bert De Rybel (B)

Ghent University, Department of Plant Biotechnology and Bioinformatics, Technologiepark 71, 9052 Ghent, Belgium.
VIB Centre for Plant Systems Biology, Technologiepark 71, 9052 Ghent, Belgium.

Teva Vernoux (T)

Laboratoire Reproduction et Développement des Plantes, University Lyon, ENS de Lyon, CNRS, INRAE, INRIA, 69342 Lyon, France.

Classifications MeSH