Mitochondrial respiratory chain dysfunction in a patient with a heterozygous de novo

CTBP1 neurodevelopmental disorder secondary mitochondrial dysfunction

Journal

JIMD reports
ISSN: 2192-8304
Titre abrégé: JIMD Rep
Pays: United States
ID NLM: 101568557

Informations de publication

Date de publication:
Nov 2022
Historique:
received: 03 06 2022
revised: 11 08 2022
accepted: 16 08 2022
entrez: 7 11 2022
pubmed: 8 11 2022
medline: 8 11 2022
Statut: epublish

Résumé

The C-terminal binding protein 1 (CTBP1) functions as a transcriptional corepressor in vertebrates and has been identified to have critical roles in nervous system growth and development. Pathogenic variants in the

Identifiants

pubmed: 36341169
doi: 10.1002/jmd2.12326
pii: JMD212326
pmc: PMC9626656
doi:

Types de publication

Case Reports

Langues

eng

Pagination

546-554

Informations de copyright

© 2022 The Authors. JIMD Reports published by John Wiley & Sons Ltd on behalf of SSIEM.

Déclaration de conflit d'intérêts

Wui‐Kwan Wong, Shanti Balasubramaniam, Rachel SH Wong, Nicole Graf, David R Thorburn, Robert McFarland, and Christopher Troedson declare that they have no conflict of interest.

Références

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Auteurs

Wui-Kwan Wong (WK)

TY Nelson Department of Neurology and Neurosurgery The Children's Hospital at Westmead Sydney New South Wales Australia.

Shanti Balasubramaniam (S)

Genetic Metabolic Disorders Service The Children's Hospital at Westmead Sydney New South Wales Australia.
Discipline of Genomic Medicine, Sydney Medical School University of Sydney Sydney New South Wales Australia.

Rachel S H Wong (RSH)

Genetic Metabolic Disorders Service The Children's Hospital at Westmead Sydney New South Wales Australia.

Nicole Graf (N)

Department of Histopathology The Children's Hospital at Westmead Sydney Australia.

David R Thorburn (DR)

Murdoch Children's Research Institute Melbourne Victoria Australia.
Department of Paediatrics University of Melbourne Melbourne Victoria Australia.
Victorian Clinical Genetics Services Melbourne Victoria Australia.

Robert McFarland (R)

Wellcome Centre for Mitochondrial Research, Translational and Clinical Research Institute, Faculty of Medical Sciences Newcastle University Newcastle upon Tyne UK.
NHS Highly Specialised Service for Rare Mitochondrial Disorders Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne UK.

Christopher Troedson (C)

TY Nelson Department of Neurology and Neurosurgery The Children's Hospital at Westmead Sydney New South Wales Australia.

Classifications MeSH