A Trans Youth of Color Study to Measure Health and Wellness: Protocol for a Longitudinal Observation Study.

AIDS virus HIV cohort study gender minority transgender youth

Journal

JMIR research protocols
ISSN: 1929-0748
Titre abrégé: JMIR Res Protoc
Pays: Canada
ID NLM: 101599504

Informations de publication

Date de publication:
07 Nov 2022
Historique:
received: 02 05 2022
accepted: 22 09 2022
revised: 29 08 2022
entrez: 7 11 2022
pubmed: 8 11 2022
medline: 8 11 2022
Statut: epublish

Résumé

Growing research on transgender youth is accounting for the variety of ways in which young people define their genders and sexualities. Because of this growing representation, more research is needed to understand how intersectional identities and stigma affect risk for HIV acquisition along the HIV care continuum and engagement in mental and physical health care. Little is known about accessibility to HIV-related prevention services of nonbinary and transmasculine youth, and further understanding of the impacts on transfeminine people-those who have historically faced the highest prevalence of HIV positivity-is crucial. The overarching aims of the Trans Youth of Color Study are to conduct longitudinal research with a cohort of transgender minority youth (TGMY), explore factors that aid in the prevention of new HIV infection and transmission, and reduce HIV- and AIDS-related disparities by focusing on successful engagement in care. Findings from this research will be used to inform the development of new interventions designed to engage TGMY in the HIV prevention and care continua. Longitudinal research (baseline and follow-up assessments every 6 months for 3 waves of data collection) followed a cohort (N=108) of transgender youth of color recruited in Los Angeles, California, United States. Participants were recruited using multiple community-informed strategies, such as from local venues, social media, and participant referral. In addition to self-report surveys, urine was collected to assess recent use of illicit drugs, and blood, rectal, and throat swabs were collected to test for current sexually transmitted infection and HIV infection. Additional blood and plasma samples (10 mL for 4 aliquots and 1 pellet) were collected and stored for future research. Participants in the Trans Youth of Color Study were recruited between May 25, 2018, and December 7, 2018. Baseline and longitudinal data are being analyzed as of August 2022. The findings from this research will inform adaptations to existing evidence-based HIV prevention interventions and help to guide new interventions designed to engage TGMY, especially those who are Black, Indigenous, or people of color, in the HIV prevention and care continua. DERR1-10.2196/39207.

Sections du résumé

BACKGROUND BACKGROUND
Growing research on transgender youth is accounting for the variety of ways in which young people define their genders and sexualities. Because of this growing representation, more research is needed to understand how intersectional identities and stigma affect risk for HIV acquisition along the HIV care continuum and engagement in mental and physical health care. Little is known about accessibility to HIV-related prevention services of nonbinary and transmasculine youth, and further understanding of the impacts on transfeminine people-those who have historically faced the highest prevalence of HIV positivity-is crucial.
OBJECTIVE OBJECTIVE
The overarching aims of the Trans Youth of Color Study are to conduct longitudinal research with a cohort of transgender minority youth (TGMY), explore factors that aid in the prevention of new HIV infection and transmission, and reduce HIV- and AIDS-related disparities by focusing on successful engagement in care. Findings from this research will be used to inform the development of new interventions designed to engage TGMY in the HIV prevention and care continua.
METHODS METHODS
Longitudinal research (baseline and follow-up assessments every 6 months for 3 waves of data collection) followed a cohort (N=108) of transgender youth of color recruited in Los Angeles, California, United States. Participants were recruited using multiple community-informed strategies, such as from local venues, social media, and participant referral. In addition to self-report surveys, urine was collected to assess recent use of illicit drugs, and blood, rectal, and throat swabs were collected to test for current sexually transmitted infection and HIV infection. Additional blood and plasma samples (10 mL for 4 aliquots and 1 pellet) were collected and stored for future research.
RESULTS RESULTS
Participants in the Trans Youth of Color Study were recruited between May 25, 2018, and December 7, 2018. Baseline and longitudinal data are being analyzed as of August 2022.
CONCLUSIONS CONCLUSIONS
The findings from this research will inform adaptations to existing evidence-based HIV prevention interventions and help to guide new interventions designed to engage TGMY, especially those who are Black, Indigenous, or people of color, in the HIV prevention and care continua.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) UNASSIGNED
DERR1-10.2196/39207.

Identifiants

pubmed: 36342757
pii: v11i11e39207
doi: 10.2196/39207
pmc: PMC9679929
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e39207

Subventions

Organisme : NIDA NIH HHS
ID : U01 DA036926
Pays : United States

Informations de copyright

©Sam Calvetti, Joshua A Rusow, Jacqueline Lewis, Amarah Martinez, Lindsay Slay, Bethany C Bray, Jeremy T Goldbach, Michele D Kipke. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 07.11.2022.

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Auteurs

Sam Calvetti (S)

Children's Hospital Los Angeles, Los Angeles, CA, United States.

Joshua A Rusow (JA)

The Brown School, Washington University in St Louis, St Louis, MO, United States.

Jacqueline Lewis (J)

Health Services, Los Angeles LGBT Center, Los Angeles, CA, United States.

Amarah Martinez (A)

HIV & Biomedical Department, Wesley Health Centers, JWCH Institute, Palmdale, CA, United States.

Lindsay Slay (L)

Children's Hospital Los Angeles, Los Angeles, CA, United States.

Bethany C Bray (BC)

Institute for Health Research and Policy, University of Illinois Chicago, Chicago, IL, United States.

Jeremy T Goldbach (JT)

The Brown School, Washington University in St Louis, St Louis, MO, United States.

Michele D Kipke (MD)

Children's Hospital Los Angeles, Los Angeles, CA, United States.
Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.

Classifications MeSH