Optic nerve cavitations in glaucoma suspect and glaucoma patients.
Glaucoma
Imaging
Intrachoroidal cavitations
Lamina cribosa
Optic nerve cavitations
Optical coherence tomography
Journal
American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
28
06
2022
revised:
18
10
2022
accepted:
19
10
2022
entrez:
8
11
2022
pubmed:
9
11
2022
medline:
9
11
2022
Statut:
epublish
Résumé
Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). OCT imaging showed cavitations in 5 eyes of 4 patients with an initial diagnosis of glaucoma or glaucoma suspect. The cavitations were seen as hyporeflective spaces that are sharply delineated from surrounding tissue. They were centered inferonasally, anterior to the lamina cribosa, and at least partially within the Bruch's membrane opening (BMO). They extended from 3 to 6 clock hours. AND IMPORTANCE: We describe a new OCT finding in patients with a diagnosis of glaucoma and glaucoma suspect. While previous reports describe cavitations in the choroid in patients with pathological myopia, our patients had minimal refractive error and the cavitations were located within the optic nerve. We will examine these patients over time to determine the impact of this finding on longitudinal changes in structure and function.
Identifiants
pubmed: 36345413
doi: 10.1016/j.ajoc.2022.101733
pii: S2451-9936(22)00479-0
pmc: PMC9636442
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101733Informations de copyright
© 2022 Published by Elsevier Inc.
Déclaration de conflit d'intérêts
No conflict of interest exists.
Références
Prog Retin Eye Res. 2017 Jul;59:1-52
pubmed: 28300644
Ophthalmology. 2016 Oct;123(10):2066-76
pubmed: 27506483
Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):2818-2827
pubmed: 29860466
Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):13
pubmed: 35446343
Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):26-35
pubmed: 30601928
Am J Ophthalmol. 2021 Mar;223:246-258
pubmed: 33166501