Infants With Congenital Heart Disease at Risk of Early Atherosclerotic Disease.
aortic intima‐media thickness
atherosclerosis
cardiovascular
congenital heart disease
Journal
Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524
Informations de publication
Date de publication:
15 11 2022
15 11 2022
Historique:
pubmed:
9
11
2022
medline:
18
11
2022
entrez:
8
11
2022
Statut:
ppublish
Résumé
Background Aortic intima-media thickness (aIMT) measurement is an established indicator of preclinical atherosclerosis. We aimed to describe the aIMT in infants with congenital heart disease undergoing cardiac surgery over the first year of life and explore its association with cardiopulmonary bypass, growth velocity, and a diagnosis of left heart obstruction. Methods and Results A prospective cohort study measuring mean and maximum aIMT preoperatively, at 3 months, and 1 year of age in neonates with congenital heart disease undergoing cardiac surgery. Twenty-four infants with a median gestation of 39 weeks and a median birth weight of 3184 g were included. Sixteen (67%) infants had left outflow tract obstruction. Gestation correlated inversely with baseline mean aIMT (β=-0.027,
Identifiants
pubmed: 36346062
doi: 10.1161/JAHA.122.025772
pmc: PMC9750076
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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