Migrant status, clinical symptoms and functional outcome in youth at clinical high risk for psychosis: findings from the NAPLS-3 study.
Clinical high risk
Functional outcome
Immigration
Psychosis
Journal
Social psychiatry and psychiatric epidemiology
ISSN: 1433-9285
Titre abrégé: Soc Psychiatry Psychiatr Epidemiol
Pays: Germany
ID NLM: 8804358
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
25
11
2021
accepted:
28
10
2022
medline:
4
4
2023
pubmed:
9
11
2022
entrez:
8
11
2022
Statut:
ppublish
Résumé
Migrant status is a known risk factor for psychosis, but the underlying causes of this vulnerability are poorly understood. Recently, studies have begun to explore whether migrant status predicts transition to psychosis in individuals at clinical high risk (CHR) for psychosis. Results, however, have been inconclusive. The present study assessed the impact of migrant status on clinical symptoms and functional outcome in individuals at CHR for psychosis who took part in the NAPLS-3 study. Participants' migrant status was classified as native-born, first-generation, or second-generation migrant. Clinical symptoms were assessed using the Structured Interview for Psychosis-Risk Syndromes (SIPS); functional outcome was measured using the Global Functioning Scales:Social and Role (GF:S; GF:R). Assessments were conducted at baseline, 12-months, 18-months, and 24-months follow-up. Generalized linear mixed models for repeated measures were used to examine changes over time and differences between groups. The overall sample included 710 individuals at CHR for psychosis (54.2% males; Age: M = 18.19; SD = 4.04). A mixed model analysis was conducted, and no significant differences between groups in symptoms or functioning were observed at any time point. Over time, significant improvement in symptoms and functioning was observed within each group. Transition rates did not differ across groups. We discuss potential factors that might explain the lack of group differences. Overall, migrants are a heterogeneous population. Discerning the impact of migration from that of neighborhood ethnic density, social disadvantage or socio-economic status of different ethnic groups could help better understand vulnerability and resilience to psychosis.
Identifiants
pubmed: 36348056
doi: 10.1007/s00127-022-02383-y
pii: 10.1007/s00127-022-02383-y
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
559-568Subventions
Organisme : NIMH NIH HHS
ID : U01MH081984
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081928
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081944
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081902
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH082004
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081988
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH082022
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH076989
Pays : United States
Organisme : NIMH NIH HHS
ID : UO1MH081857
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081984
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081928
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081944
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081902
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081902
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH082004
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH081988
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH082022
Pays : United States
Organisme : NIMH NIH HHS
ID : U01MH076989
Pays : United States
Organisme : NIMH NIH HHS
ID : UO1MH081857
Pays : United States
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.
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