Aging, Equality and the Human Healthspan.

Aging Equality Healthspan Life extension

Journal

HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues
ISSN: 1572-8498
Titre abrégé: HEC Forum
Pays: Netherlands
ID NLM: 8917455

Informations de publication

Date de publication:
08 Nov 2022
Historique:
accepted: 12 10 2022
entrez: 8 11 2022
pubmed: 9 11 2022
medline: 9 11 2022
Statut: aheadofprint

Résumé

John Davis (New Methuselahs: The Ethics of Life Extension, The MIT Press, Cambridge, 2018) advances a novel ethical analysis of longevity science that employs a three-fold methodology of examining the impact of life extension technologies on three distinct groups: the "Haves", the "Have-nots" and the "Will-nots". In this essay, I critically examine the egalitarian analysis Davis deploys with respect to its ability to help us theorize about the moral significance of an applied gerontological intervention. Rather than focusing on futuristic scenarios of radical life extension, I offer a rival egalitarian analysis that takes seriously (1) the health vulnerabilities of today's aging populations, (2) the health inequalities of the "aging status quo" and, (3) the prospects for the fair diffusion of an aging intervention over the not-so-distant future. Despite my reservations about Davis's focus on "life-extension" vs. increasing the human "healthspan", I agree with his central conclusion that an aging intervention would be, on balance, a good thing and that we should fund such research aggressively. But, I make an even stronger case and conjecture that an intervention that slows down the rate of molecular and cellular decline from the inborn aging process will likely be one of the most important public health advancements of the twenty-first century. This is so because aging is the most prevalent risk factor for chronic disease, frailty and disability, and it is estimated that there will be over 2 billion persons age > 60 by the year 2050.

Identifiants

pubmed: 36348214
doi: 10.1007/s10730-022-09499-3
pii: 10.1007/s10730-022-09499-3
pmc: PMC9644010
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature B.V.

Références

PLoS One. 2013 Jun 18;8(6):e66550
pubmed: 23823705
Lancet. 1999 Dec;354 Suppl:SIV4
pubmed: 10691452
Lancet. 1998 May 23;351(9115):1560
pubmed: 10326548
JAMA. 2018 Oct 2;320(13):1323-1324
pubmed: 30242384
Milbank Q. 2005;83(4):801-23
pubmed: 16279968
Curr Biol. 2012 Sep 25;22(18):R792-3
pubmed: 23017989
Biogerontology. 2003;4(1):31-45
pubmed: 12652187
Aging Dis. 2020 Jul 23;11(4):725-729
pubmed: 32765937
Geroscience. 2018 Aug;40(4):361-364
pubmed: 30084059
Nature. 1977 Nov 24;270(5635):301-4
pubmed: 593350
Obes Rev. 2020 Apr;21(4):e12991
pubmed: 32020741
BMJ. 2008 Jul 08;337:a399
pubmed: 18614506
Lancet. 2017 Jul 29;390(10093):500-509
pubmed: 28792412
Cell. 2014 Nov 6;159(4):709-13
pubmed: 25417146
Nature. 2009 Jul 16;460(7253):392-5
pubmed: 19587680
Clin Geriatr Med. 2008 Aug;24(3):395-405, v
pubmed: 18672179
Proc R Soc Lond B Biol Sci. 1979 Sep 21;205(1161):531-46
pubmed: 42059
Cold Spring Harb Perspect Med. 2016 Mar 01;6(3):a025932
pubmed: 26931809
Nat Aging. 2021 Mar;1(3):295-308
pubmed: 33796868
Aging Cell. 2020 Oct;19(10):e13230
pubmed: 33006233
J Gerontol A Biol Sci Med Sci. 2003 Mar;58(3):232-7
pubmed: 12634289
Nature. 2000 Nov 9;408(6809):233-8
pubmed: 11089980
Biogerontology. 2010 Jun;11(3):377-85
pubmed: 19890732
J Am Geriatr Soc. 2004 Feb;52(2):274-7
pubmed: 14728640
Science. 2015 Dec 4;350(6265):1191-3
pubmed: 26785476
Geroscience. 2021 Jun;43(3):1135-1158
pubmed: 33037985
Science. 2007 Sep 7;317(5843):1351-4
pubmed: 17823345
J Gerontol. 1969 Oct;24(4):395-411
pubmed: 5362349
Ann N Y Acad Sci. 2000 Jun;908:282-90
pubmed: 10911967

Auteurs

Colin Farrelly (C)

Department of Political Studies, Queen's University, Kingston, ON, Canada. farrelly@queensu.ca.

Classifications MeSH