ER-endosome contacts master the ins and outs of secretory endosomes.

Biological Transport Cell Membrane / metabolism Endosomes / metabolism Exosomes Endoplasmic Reticulum / metabolism

Journal

The Journal of cell biology
ISSN: 1540-8140
Titre abrégé: J Cell Biol
Pays: United States
ID NLM: 0375356

Informations de publication

Date de publication:
05 12 2022
Historique:
entrez: 10 11 2022
pubmed: 11 11 2022
medline: 15 11 2022
Statut: ppublish

Résumé

What defines whether an endosome follows the degradative pathway or fuses with the plasma membrane to release exosomes? In this issue of JCB, Fredrik Verweij and colleagues (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202112032) demonstrate how secretory endosomes are guided by ER-endosome contacts to take a cellular detour and several identity transitions for efficient exosome release.

Identifiants

DOI: 10.1083/jcb.202210033 PMID: 36355088 PMC: PMC9652769
pubmed: 36355088
pii: 213676
doi: 10.1083/jcb.202210033
pmc: PMC9652769
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Comment

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentOn

Informations de copyright

© 2022 Wenzel and Raiborg.

Références

J Cell Biol. 2009 Jun 29;185(7):1209-25
pubmed: 19564404
Annu Rev Cell Dev Biol. 2016 Oct 6;32:143-171
pubmed: 27576122
J Cell Biol. 2022 Dec 5;221(12):
pubmed: 36136097
Nat Rev Mol Cell Biol. 2018 Apr;19(4):213-228
pubmed: 29339798
Trends Cell Biol. 2017 Aug;27(8):580-594
pubmed: 28363667
J Cell Biol. 2022 Dec 5;221(12):
pubmed: 36355088
Nat Rev Mol Cell Biol. 2018 Nov;19(11):679-696
pubmed: 30194414

Auteurs

Eva Maria Wenzel (EM)

Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Montebello, Oslo, Norway.
Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello, Oslo, Norway.
ORCID: 0000-0002-5561-3344

Camilla Raiborg (C)

Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Montebello, Oslo, Norway.
Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Montebello, Oslo, Norway.
ORCID: 0000-0002-5406-5403

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Transport biologique › ER-endosome contacts master the ins and outs...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › ER-endosome contacts master the ins and outs...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Endosomes › ER-endosome contacts master the ins and outs...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Exosomes › ER-endosome contacts master the ins and outs...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Réticulum endoplasmique › ER-endosome contacts master the ins and outs...