The Impact of Organ Procurement Injury on Transplant Organ Availability.


Journal

Transplantation proceedings
ISSN: 1873-2623
Titre abrégé: Transplant Proc
Pays: United States
ID NLM: 0243532

Informations de publication

Date de publication:
Oct 2022
Historique:
received: 11 02 2022
revised: 10 05 2022
accepted: 16 06 2022
pubmed: 11 11 2022
medline: 7 12 2022
entrez: 10 11 2022
Statut: ppublish

Résumé

Patients on the transplant waiting list continue to have a significant wait time as organ supply remains low. Many initiatives have been undertaken in the last few years to attempt to increase the organ allograft supply. As organ procurement organizations have attempted to increase their procurement of organs from deceased donors, emphasis has been placed on avoidance of injury to organs during procurement. To analyze the success of this attention, data were collected from 29 of 57 organ procurement organizations in the United States. Data collection was from November 2017 to January 2020. Total injury rate ranged from 6% (donation after brain death) to 8.4% (donation after circulatory death). Level 3 injuries, those resulting in loss of the allograft, ranged from 1.1% in donation after brain death to 1.6% in donation after circulatory death. The most likely injured organ resulting in loss of viability (level 3 injury) during procurement was the right kidney. We noted that among donors with procurement injuries, a higher number had no previous abdominal surgery and there were more injuries noted from attending surgeons (compared to trainees). Deceased donor procurement organ injuries, though rare, lead to substantial loss of transplantable organs every year. Given that the United Network for Organ Sharing has recorded >10,000 deceased donors yearly for the past few years, such injuries can result in hundreds of transplantable organs lost. In this article we detailed the incidence and degree of injury and some variables that may be associated with these injuries.

Identifiants

pubmed: 36357226
pii: S0041-1345(22)00497-3
doi: 10.1016/j.transproceed.2022.06.008
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2075-2081

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Elizabeth Taber-Hight (E)

Indiana University Division of Nephrology, Department of Medicine, Indianapolis, Indiana. Electronic address: ebtaber@iu.edu.

Anil Paramesh (A)

Louisiana Organ Procurement Agency, New Orleans, Louisiana.

Nikole Neidlinger (N)

Department of Surgery, University of Wisconsin, Madison, Wisconsin.

Daniel J Lebovitz (DJ)

Pediatric Critical Care, Akron Childrens' Hospital, Akron, Ohio.

Michael Souter (M)

Medical Director LifeCenter Northwest, Harborview Medical Center; Anesthesia and Pain Medicine; University of Washington, Seattle, Washington.

Tim Taber (T)

Indiana University Division of Nephrology, Department of Medicine, Indianapolis, Indiana.

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