Parakinesia: A Delphi consensus report.

Endogenous psychoses Grimacing Mannerism Neuropsychiatry Parakinesia Periodic catatonia Psychomotor phenomena Schizophrenia Schizophrenia spectrum disorders Tardive dyskinesia Wernicke–Kleist–Leonhard school

Journal

Schizophrenia research
ISSN: 1573-2509
Titre abrégé: Schizophr Res
Pays: Netherlands
ID NLM: 8804207

Informations de publication

Date de publication:
07 Nov 2022
Historique:
received: 21 07 2022
revised: 22 09 2022
accepted: 22 09 2022
entrez: 10 11 2022
pubmed: 11 11 2022
medline: 11 11 2022
Statut: aheadofprint

Résumé

Abnormal movements are intrinsic to some forms of endogenous psychoses. Spontaneous dyskinesias are observed in drug-naïve first-episode patients and at-risk subjects. However, recent descriptions of spontaneous dyskinesias may actually represent the rediscovery of a more complex phenomenon, 'parakinesia' which was described and documented in extensive cinematographic recordings and long-term observations by German and French neuropsychiatrists decades before the introduction of antipsychotics. With the emergence of drug induced movement disorders, the description of parakinesia has been refined to emphasize the features enabling differential diagnosis with tardive dyskinesia. Unfortunately, parakinesia was largely neglected by mainstream psychiatry to the point of being almost absent from the English-language literature. With the renewed interest in motor phenomena intrinsic to SSD, it was timely not only to raise awareness of parakinesia, but also to propose a scientifically usable definition for this phenomenon. Therefore, we conducted a Delphi consensus exercise with clinicians familiar with the concept of parakinesia. The original concept was separated into hyperkinetic parakinesia (HPk) as dyskinetic-like expressive movements and parakinetic psychomotricity (PPM), i.e., patient's departing from the patient's normal motion style. HPk prevails on the upper part of the face and body, resembling expressive and reactive gestures that not only occur inappropriately but also appear distorted. Abnormal movements vary in intensity depending on the level of psychomotor arousal and are thus abated by antipsychotics. HPk frequently co-occurs with PPM, in which gestures and mimics lose their naturalness and become awkward, disharmonious, stiff, mannered, and bizarre. Patients are never spontaneously aware of HPk or PPM, and the movements are never experienced as self-dystonic or self-alien. HPk and PPM are highly specific to endogenous psychoses, in which they are acquired and progressive, giving them prognostic value. Their differential diagnoses and correspondences with current international concepts are discussed.

Identifiants

pubmed: 36357299
pii: S0920-9964(22)00366-8
doi: 10.1016/j.schres.2022.09.024
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2022. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as potential conflicts of interest.

Auteurs

Jack R Foucher (JR)

ICube - CNRS UMR 7357, Neurophysiology, FMTS, University of Strasbourg, France; CEMNIS - Noninvasive Neuromodulation Center, University Hospital Strasbourg, France. Electronic address: jack.foucher@unistra.fr.

Andreas J Bartsch (AJ)

Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany.

Olivier Mainberger (O)

ICube - CNRS UMR 7357, Neurophysiology, FMTS, University of Strasbourg, France; CEMNIS - Noninvasive Neuromodulation Center, University Hospital Strasbourg, France.

Laurent Vercueil (L)

Clinical Neurophysiology Unit, Univ. Grenoble Alpes, INSERM U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, Grenoble, France.

Clément C de Billy (CC)

ICube - CNRS UMR 7357, Neurophysiology, FMTS, University of Strasbourg, France; CEMNIS - Noninvasive Neuromodulation Center, University Hospital Strasbourg, France.

Alexandre Obrecht (A)

ICube - CNRS UMR 7357, Neurophysiology, FMTS, University of Strasbourg, France; CEMNIS - Noninvasive Neuromodulation Center, University Hospital Strasbourg, France.

Hippolyte Arcay (H)

ICube - CNRS UMR 7357, Neurophysiology, FMTS, University of Strasbourg, France.

Fabrice Berna (F)

Pôle de Psychiatrie, Santé Mentale et Addictologie, University Hospital Strasbourg, France; Physiopathologie et Psychopathologie Cognitive de la Schizophrénie - INSERM 1114, FMTS, University of Strasbourg, France.

Julie M E Clauss (JME)

Pôle de Psychiatrie, Santé Mentale et Addictologie, University Hospital Strasbourg, France; SAGE - CNRS UMR 7363, FMTS, University of Strasbourg, France.

Sébastien Weibel (S)

Pôle de Psychiatrie, Santé Mentale et Addictologie, University Hospital Strasbourg, France; Physiopathologie et Psychopathologie Cognitive de la Schizophrénie - INSERM 1114, FMTS, University of Strasbourg, France.

Markus Hanke (M)

University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Switzerland.

Julien Elowe (J)

Department of Psychiatry, Prangins Psychiatric Hospital (CHUV), Prangins, Switzerland.

Benoit Schorr (B)

Pôle de Psychiatrie, Santé Mentale et Addictologie, University Hospital Strasbourg, France; Physiopathologie et Psychopathologie Cognitive de la Schizophrénie - INSERM 1114, FMTS, University of Strasbourg, France.

Efflam Bregeon (E)

Pôle de Psychiatrie, University Hospital Angers, France.

Birgit Braun (B)

Abteilung für Psychosomatische Medizin und Psychotherapie, Universitätsklinikum Regensburg, Germany.

Marcelo Cetkovich (M)

Institute of Translational and Cognitive Neuroscience (INCyT), INECO Foundation, Favaloro University, Buenos Aires, Argentina; National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.

Burkhard E Jabs (BE)

Klinik für Psychiatrie & Psychotherapie, Städtisches Klinikum Dresden, Dresden, Germany.

Thomas Dorfmeister (T)

Abteilung für Psychiatrie und psychotherapeutische Medizin, Landesklinikum Neunkirchen, Austria.

Gabor S Ungvari (GS)

Section of Psychiatry, University Notre Dame, Fremantle, Australia; Division of Psychiatry, School of Medicine, University of Western Australia, Crawley, WA, Australia.

Ludovic C Dormegny-Jeanjean (LC)

ICube - CNRS UMR 7357, Neurophysiology, FMTS, University of Strasbourg, France; CEMNIS - Noninvasive Neuromodulation Center, University Hospital Strasbourg, France.

Bruno Pfuhlmann (B)

Klinik für Psychiatrie & Psychotherapie, Städtisches Klinikum Dresden, Dresden, Germany.

Classifications MeSH