Nanoscale Contrast Agents for Ultrasound Imaging of Musculoskeletal System.

molecular imaging musculoskeletal ultrasound nanotechnology ultrasound contrast agent ultrasound imaging

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
25 Oct 2022
Historique:
received: 28 08 2022
revised: 09 10 2022
accepted: 12 10 2022
entrez: 11 11 2022
pubmed: 12 11 2022
medline: 12 11 2022
Statut: epublish

Résumé

Musculoskeletal ultrasound (MSKUS) has been recognized as an important method for the evaluation of diseases of the musculoskeletal system, and contrast-enhanced ultrasound (CEUS) technology is becoming an important branch of it. The development of novel materials and tiny nano-formulations has further expanded ultrasound contrast agents (UCAs) into the field of nanotechnology. Over the years, nanoscale contrast agents have been found to play an unexpected role in the integration of precise imaging for diagnosis and treatment of numerous diseases. It has been demonstrated that nanoscale UCAs (nUCAs) have advantages in imaging over conventional contrast agents, including superior biocompatibility, serum stability, and longer lifetime. The potential value of nUCAs in the musculoskeletal system is that they provide more reliable and clinically valuable guidance for the diagnosis, treatment, and follow-up of related diseases. The frontier of advances in nUCAs, their applications, and insights in MSKUS are reviewed in this paper.

Identifiants

pubmed: 36359426
pii: diagnostics12112582
doi: 10.3390/diagnostics12112582
pmc: PMC9689263
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : National Natural Science Foundation of China
ID : 81501492
Organisme : Natural Science Foundation of Shanghai of China
ID : 20ZR1457900

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Auteurs

Xiaoyi Tang (X)

Department of Ultrasound, Changzheng Hospital, Naval Medical University (Second Military Medical University), Shanghai 200003, China.

Mengxin Zhao (M)

Shanghai Key Lab of Cell Engineering, Department of Nanomedicine, Naval Medical University (Second Military Medical University), Shanghai 200433, China.

Wei Li (W)

Shanghai Key Lab of Cell Engineering, Department of Nanomedicine, Naval Medical University (Second Military Medical University), Shanghai 200433, China.

Jiaqi Zhao (J)

Department of Ultrasound, Changzheng Hospital, Naval Medical University (Second Military Medical University), Shanghai 200003, China.

Classifications MeSH