Nogo-A Regulates the Fate of Human Dental Pulp Stem Cells toward Osteogenic, Adipogenic, and Neurogenic Differentiation.
Nogo-A
adipogenic potential
anti-Nogo-A antibody
dental pulp
differentiation
human
human dental pulp stem cells
in vitro
neurogenic potential
osteogenic potential
single cell RNA sequencing
stem cell fates
tooth
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
28 10 2022
28 10 2022
Historique:
received:
20
07
2022
revised:
24
08
2022
accepted:
26
10
2022
entrez:
11
11
2022
pubmed:
12
11
2022
medline:
15
11
2022
Statut:
epublish
Résumé
Human teeth are highly innervated organs that contain a variety of mesenchymal stem cell populations that could be used for cell-based regenerative therapies. Specific molecules are often used in these treatments to favorably modulate the function and fate of stem cells. Nogo-A, a key regulator of neuronal growth and differentiation, is already used in clinical tissue regeneration trials. While the functions of Nogo-A in neuronal tissues are extensively explored, its role in teeth still remains unknown. In this work, we first immunohistochemically analyzed the distribution of Nogo-A protein in the dental pulp of human teeth. Nogo-A is localized in a variety of cellular and structural components of the dental pulp, including odontoblasts, fibroblasts, neurons and vessels. We also cross-examined
Identifiants
pubmed: 36359811
pii: cells11213415
doi: 10.3390/cells11213415
pmc: PMC9657129
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Stem Cells Transl Med. 2013 Jul;2(7):521-33
pubmed: 23761108
EMBO Rep. 2004 Sep;5(9):867-71
pubmed: 15470383
Stem Cells Dev. 2019 May 15;28(10):695-706
pubmed: 30887879
J Dent Res. 2002 Aug;81(8):531-5
pubmed: 12147742
Cell. 2007 Feb 23;128(4):707-19
pubmed: 17320508
J Immunol Res. 2014;2014:987678
pubmed: 24741639
Science. 2000 Feb 25;287(5457):1427-30
pubmed: 10688781
Gene Expr Patterns. 2005 Apr;5(4):561-8
pubmed: 15749087
NPJ Regen Med. 2021 Apr 12;6(1):24
pubmed: 33846347
PLoS Biol. 2014 Jan;12(1):e1001763
pubmed: 24453941
Int J Mol Sci. 2021 Mar 16;22(6):
pubmed: 33809663
Exp Cell Res. 2003 Jan 15;282(2):101-9
pubmed: 12531696
Int J Biochem Cell Biol. 2004 Apr;36(4):568-84
pubmed: 15010324
Cell Stem Cell. 2013 Feb 7;12(2):152-65
pubmed: 23395443
Stem Cell Res Ther. 2021 May 29;12(1):302
pubmed: 34051821
J Dent Res. 2004 Dec;83(12):896-902
pubmed: 15557394
Stem Cell Res Ther. 2018 Apr 27;9(1):116
pubmed: 29703239
BMC Neurosci. 2009 Mar 03;10:16
pubmed: 19257891
Exp Cell Res. 2015 Dec 10;339(2):231-40
pubmed: 26586565
Neuron. 2005 Feb 3;45(3):345-51
pubmed: 15694321
Stem Cell Res Ther. 2016 Jul 28;7(1):97
pubmed: 27465541
Differentiation. 2020 May - Jun;113:38-48
pubmed: 32403041
Nature. 2000 Jan 27;403(6768):434-9
pubmed: 10667796
J Bone Miner Res. 2003 Apr;18(4):696-704
pubmed: 12674330
FASEB J. 2019 Jun;33(6):6689-6696
pubmed: 30811954
Curr Opin Immunol. 1997 Apr;9(2):216-21
pubmed: 9099790
Regen Med. 2018 Sep;13(6):741-752
pubmed: 30043682
Eur Cell Mater. 2008 Jul 31;16:1-9
pubmed: 18671204
Eur Cell Mater. 2015 Mar 20;29:213-23
pubmed: 25794530
J Orthop Surg Res. 2010 Jun 15;5:37
pubmed: 20550694
Nature. 2010 Jun 10;465(7299):713-20
pubmed: 20535200
Autophagy. 2022 Nov;18(11):2711-2730
pubmed: 35263212
Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):1577-1584
pubmed: 31027424
Eur Cell Mater. 2010 Sep 01;20:121-33
pubmed: 21249629
Nat Neurosci. 2003 May;6(5):461-7
pubmed: 12692556
J Dent Res. 2016 Feb;95(2):206-14
pubmed: 26494655
Stem Cells. 2007 Nov;25(11):2739-49
pubmed: 17656645
Biochem Biophys Res Commun. 2016 Apr 29;473(2):482-9
pubmed: 26987715
Nat Neurosci. 2004 Mar;7(3):221-8
pubmed: 14966521
Int J Mol Sci. 2020 Aug 26;21(17):
pubmed: 32859105
Exp Biol Med (Maywood). 2001 Dec;226(11):997-1002
pubmed: 11743135
Biomedicines. 2022 May 03;10(5):
pubmed: 35625792
Cells. 2021 Jan 31;10(2):
pubmed: 33572505
Nat Commun. 2021 Nov 25;12(1):6906
pubmed: 34824275
Lancet. 2018 Mar 3;391(10123):883-910
pubmed: 28987452
Sci Rep. 2018 Sep 10;8(1):13551
pubmed: 30202094
Nature. 2014 Jan 16;505(7483):327-34
pubmed: 24429631
Cells. 2019 Oct 22;8(10):
pubmed: 31652655
Ann Neurol. 2010 Apr;67(4):498-507
pubmed: 20437585
Eur Cell Mater. 2014 Oct 06;28:166-207; discussion 207-8
pubmed: 25284140
Stem Cells Int. 2015;2015:628368
pubmed: 25767512
Sci Rep. 2019 Feb 11;9(1):1761
pubmed: 30741963
Front Physiol. 2018 Aug 08;9:1102
pubmed: 30135661
Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14270-14279
pubmed: 31235580
Curr Protoc Stem Cell Biol. 2014 May 16;29:1H.7.1-14
pubmed: 24838914
J Neurosci. 2012 Dec 5;32(49):17788-99
pubmed: 23223298
Stem Cell Res Ther. 2017 Mar 9;8(1):61
pubmed: 28279187
PLoS One. 2021 May 6;16(5):e0251356
pubmed: 33956879
Nat Protoc. 2008;3(6):1101-8
pubmed: 18546601
Orthod Craniofac Res. 2005 Aug;8(3):191-9
pubmed: 16022721
Int J Neurosci. 2020 Feb;130(2):107-116
pubmed: 31599165
Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8352-7
pubmed: 10890885
Curr Opin Neurobiol. 2014 Aug;27:53-60
pubmed: 24632308
Cytometry A. 2013 Jan;83(1):48-61
pubmed: 23027703
Proc Natl Acad Sci U S A. 2003 May 13;100(10):5807-12
pubmed: 12716973
Neuroscientist. 2001 Oct;7(5):377-86
pubmed: 11597097
Nat Rev Mol Cell Biol. 2011 Feb;12(2):126-31
pubmed: 21253000
Eur Cell Mater. 2021 May 10;41:502-516
pubmed: 33970477
Int J Mol Sci. 2020 Jul 30;21(15):
pubmed: 32751444
Adv Exp Med Biol. 2010;658:43-9
pubmed: 19950014
Atherosclerosis. 2014 Dec;237(2):597-608
pubmed: 25463094
Biomedicines. 2020 Nov 09;8(11):
pubmed: 33182239
Development. 2016 Jul 1;143(13):2273-80
pubmed: 27381225
Biochim Biophys Acta. 2009 Jun;1791(6):479-85
pubmed: 19168150
Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2569-74
pubmed: 21262805
Biosens Bioelectron. 2022 Jun 15;206:114134
pubmed: 35276463
Int J Oral Sci. 2019 Aug 19;11(3):23
pubmed: 31423011
Cold Spring Harb Perspect Biol. 2012 Apr 01;4(4):a008425
pubmed: 22415375
Eur Cell Mater. 2015 Nov 12;30:248-57
pubmed: 26562631
Stem Cells Transl Med. 2021 Oct;10(10):1433-1445
pubmed: 34227747
Exp Cell Res. 2007 Oct 1;313(16):3377-85
pubmed: 17764674
Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1943-52
pubmed: 23625008
Bone. 2013 Oct;56(2):255-65
pubmed: 23800517
Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13625-30
pubmed: 11087820
J Mol Histol. 2021 Jun;52(3):521-537
pubmed: 33555537
Regen Med. 2008 Jan;3(1):1-5
pubmed: 18154457
Am J Med. 2018 Dec;131(12):1425-1430
pubmed: 29969611
Nat Med. 2006 Jul;12(7):790-2
pubmed: 16819551
Front Mol Neurosci. 2017 Jun 28;10:199
pubmed: 28701917
Cell Mol Neurobiol. 2022 Nov;42(8):2439-2448
pubmed: 34224050
Cell. 2002 Jan 11;108(1):17-29
pubmed: 11792318
Tissue Eng Part A. 2019 Aug;25(15-16):1067-1071
pubmed: 31115267
Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15128-15133
pubmed: 31289228
Sci Rep. 2019 Apr 1;9(1):5430
pubmed: 30931957
iScience. 2021 Apr 23;24(5):102405
pubmed: 33997688
NPJ Regen Med. 2019 Dec 2;4:22
pubmed: 31815001
Nature. 2001 Jan 18;409(6818):341-6
pubmed: 11201742
Neuron. 2005 Feb 3;45(3):353-9
pubmed: 15694322
Nat Rev Genet. 2007 Feb;8(2):93-103
pubmed: 17230196
J Integr Neurosci. 2020 Dec 30;19(4):651-662
pubmed: 33378839
Nature. 2002 Nov 7;420(6911):74-8
pubmed: 12422217
Neurorehabil Neural Repair. 2018 Jun;32(6-7):578-589
pubmed: 29869587
Nature. 2018 May;557(7705):335-342
pubmed: 29769665
Clin Epigenetics. 2021 Jul 23;13(1):144
pubmed: 34301318
Oncol Lett. 2022 May 27;24(1):230
pubmed: 35720478
Nature. 2018 May;557(7705):322-328
pubmed: 29769669
Sci Rep. 2017 May 2;7(1):1327
pubmed: 28465581
J Neurosci. 2003 Jul 2;23(13):5393-406
pubmed: 12843238
Mol Med Rep. 2020 Jan;21(1):77-88
pubmed: 31746353
Adv Dent Res. 2011 Jul;23(3):275-9
pubmed: 21677078
Nat Med. 2011 Nov 07;17(11):1437-43
pubmed: 22064433
Front Bioeng Biotechnol. 2020 Aug 14;8:983
pubmed: 32923438
Front Cell Dev Biol. 2022 Feb 14;9:820105
pubmed: 35237613
Science. 2014 Jun 13;344(6189):1250-5
pubmed: 24926013
Life Sci. 2019 Sep 1;232:116676
pubmed: 31340165
Biochem Pharmacol. 2016 Jan 15;100:28-39
pubmed: 26348872
Curr Oral Health Rep. 2018;5(4):295-303
pubmed: 30524931
Eur Cell Mater. 2009 Nov 12;18:75-83
pubmed: 19908196
Differentiation. 1992 Jan;49(1):47-61
pubmed: 1320577
Eur J Oral Sci. 2018 Oct;126 Suppl 1:67-71
pubmed: 30178557
Neuroscience. 2020 Nov 21;449:21-34
pubmed: 33039527
Histol Histopathol. 2013 Sep;28(9):1109-16
pubmed: 23588700