Gut Microbiome and Its Cofactors Are Linked to Lipoprotein Distribution Profiles.

1H-NMR HDL SCFAs gut microbiota lipoproteins distribution

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
31 Oct 2022
Historique:
received: 27 09 2022
revised: 20 10 2022
accepted: 28 10 2022
entrez: 11 11 2022
pubmed: 12 11 2022
medline: 12 11 2022
Statut: epublish

Résumé

Increasing evidence indicates that the gut microbiome (GM) plays an important role in dyslipidemia. To date, however, no in-depth characterization of the associations between GM with lipoproteins distributions (LPD) among adult individuals with diverse BMI has been conducted. To determine such associations, we studied blood-plasma LPD, fecal short-chain fatty acids (SCFA) and GM of 262 Danes aged 19-89 years. Stratification of LPD segregated subjects into three clusters displaying recommended levels of lipoproteins and explained by age and body-mass-index. Higher levels of HDL2a and HDL2b were associated with a higher abundance of

Identifiants

pubmed: 36363749
pii: microorganisms10112156
doi: 10.3390/microorganisms10112156
pmc: PMC9699503
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Innovation Fund Denmark
ID : 4105-00015B

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Auteurs

Josué L Castro-Mejía (JL)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.

Bekzod Khakimov (B)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.

Violetta Aru (V)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.

Mads V Lind (MV)

Department of Nutrition, Exercise and Sports, University of Copenhagen, 1958 Frederiksberg C, Denmark.

Eva Garne (E)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.
Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark.

Petronela Paulová (P)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.
Biomedical Research Center, Institute of Experimental Endocrinology, University Science Park for Biomedicine, Dúbravská cesta 9, 94505 Bratislava, Slovakia.

Elnaz Tavakkoli (E)

Swammerdam Institute for Life Sciences, University of Amsterdam, Postbus 94215, 1090 GE Amsterdam, The Netherlands.

Lars H Hansen (LH)

Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.

Age K Smilde (AK)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.
Swammerdam Institute for Life Sciences, University of Amsterdam, Postbus 94215, 1090 GE Amsterdam, The Netherlands.

Lars Holm (L)

Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark.
School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Søren B Engelsen (SB)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.

Dennis S Nielsen (DS)

Department of Food Science, University of Copenhagen, 1958 Frederiksberg C, Denmark.

Classifications MeSH