Krill oil protects dopaminergic neurons from age-related degeneration through temporal transcriptome rewiring and suppression of several hallmarks of aging.
aging
healthspan
krill oil
mitochondrial health
senescence
Journal
Aging
ISSN: 1945-4589
Titre abrégé: Aging (Albany NY)
Pays: United States
ID NLM: 101508617
Informations de publication
Date de publication:
09 11 2022
09 11 2022
Historique:
received:
28
07
2022
accepted:
27
10
2022
pubmed:
12
11
2022
medline:
23
11
2022
entrez:
11
11
2022
Statut:
ppublish
Résumé
There is accumulating evidence that interfering with the basic aging mechanisms can enhance healthy longevity. The interventional/therapeutic strategies targeting multiple aging hallmarks could be more effective than targeting one hallmark. While health-promoting qualities of marine oils have been extensively studied, the underlying molecular mechanisms are not fully understood. Lipid extracts from Antarctic krill are rich in long-chain omega-3 fatty acids choline, and astaxanthin. Here, we used
Identifiants
pubmed: 36367773
pii: 204375
doi: 10.18632/aging.204375
pmc: PMC9699765
doi:
Substances chimiques
Plant Oils
0
Dopamine
VTD58H1Z2X
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
8661-8687Références
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