Hemodynamic response to intestinal pH stimulation measured with spectroscopic video imaging.
blood proteome analysis
gut-skin axis
hemodynamic response
spectroscopic video imaging
Journal
Biomedical physics & engineering express
ISSN: 2057-1976
Titre abrégé: Biomed Phys Eng Express
Pays: England
ID NLM: 101675002
Informations de publication
Date de publication:
23 11 2022
23 11 2022
Historique:
received:
05
07
2022
accepted:
11
11
2022
pubmed:
12
11
2022
medline:
25
11
2022
entrez:
11
11
2022
Statut:
epublish
Résumé
To investigate the relationship between the gut and skin (gut-skin axis), head skin hemodynamic responses to gut stimulation including the injection of acetic acid in nude mice were measured by spectroscopic video imaging, which was calculated using a modified Beer-Lambert formula. The relationship with blood proteins was also analyzed. The blood volume changes in three mice injected with acetic acid were highly reproducible in the mathematical model equation. Four proteins correlated with blood volume changes were all related to immunity. These results suggest that intestinal pH can alter the blood volume in the skin and induce immune-related responses.
Identifiants
pubmed: 36368027
doi: 10.1088/2057-1976/aca20a
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Creative Commons Attribution license.