Virtual non-contrast reconstructions improve differentiation between vascular enhancement and calcifications in stereotactic planning CT scans of cystic intracranial tumors.
Dual-energy computed tomography
Intracranial cysts
Intracranial tumors
Spectral computed tomography
Stereotactic surgery
Virtual non-contrast imaging
Journal
European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
03
08
2022
revised:
13
10
2022
accepted:
26
10
2022
pubmed:
14
11
2022
medline:
6
12
2022
entrez:
13
11
2022
Statut:
ppublish
Résumé
To assess the diagnostic value of spectral-detector CT (SDCT) derived virtual non-contrast images (VNC) for differentiation between vascular enhancement and wall calcifications of cystic intracranial tumors in contrast-enhanced stereotactic planning examinations. 48 patients with cystic intracranial tumors who underwent stereotactic SDCT examinations between 02/2017 and 02/2020 were retrospectively included. In each patient, two separate hyperattenuating structures along the cyst wall were defined as either enhancement or calcification, respectively, using reference MRI examinations. Quantitative analysis was performed ROI-based in conventional images (CI) and VNC. In the subjective analysis, two radiologists diagnosed the predefined peri-cystic structures in binary decisions as either enhancement or calcification using CI and the combination of CI and VNC, and rated diagnostic confidence, image noise and removal of iodine in VNC. Moreover, a potential diagnostic benefit of VNC was indicated. Attenuation in CI was higher as compared to VNC across all assessed ROI (all p < 0.01). In VNC, CNR between calcification and white matter was significantly higher as compared to CNR between vascular enhancement and white matter (2.6 vs 1.3, p < 0.01), while there was no significant difference in CI. In the qualitative assessment, diagnostic accuracy was significantly higher using both VNC and CI compared to using CI alone. Raters reported less image noise in VNC as compared to CI. An additional diagnostic benefit of VNC was indicated in 84.4 % of all cases. SDCT-derived VNC images facilitate differentiation between peri-cystic contrast enhancement in blood vessels and calcifications in stereotactic planning scans of cystic intracranial tumors.
Identifiants
pubmed: 36371948
pii: S0720-048X(22)00433-8
doi: 10.1016/j.ejrad.2022.110583
pii:
doi:
Substances chimiques
Iodine
9679TC07X4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110583Informations de copyright
Copyright © 2022 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: [Nils Große Hokamp, David Zopfs: Receive research support from Philips Healthcare. Nils Große Hokamp, David Zopfs and David Maintz: On the speakers bureau of Philips Healthcare. Nils Große Hokamp: Consultant to Bristol-Myers Squibb.].