Increasing Use Of Interferon Gamma Release Assays Among Children ≥2 Years of Age in a Setting With Low Tuberculosis Prevalence.


Journal

The Pediatric infectious disease journal
ISSN: 1532-0987
Titre abrégé: Pediatr Infect Dis J
Pays: United States
ID NLM: 8701858

Informations de publication

Date de publication:
01 12 2022
Historique:
entrez: 14 11 2022
pubmed: 15 11 2022
medline: 18 11 2022
Statut: ppublish

Résumé

US guidelines recommend interferon gamma release assays (IGRAs) for diagnosis of tuberculosis infection in children. In this retrospective cohort study, IGRA use in children 2-17 years of age increased substantially between 2015 and 2021. Testing in inpatient/subspecialty settings (vs. primary care), public (vs. private) insurance, lower age and non-English preferred language were associated with increased odds of receiving an IGRA.

Identifiants

pubmed: 36375104
doi: 10.1097/INF.0000000000003685
pii: 00006454-202212000-00026
pmc: PMC10332931
mid: NIHMS1914948
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e534-e537

Subventions

Organisme : NIMH NIH HHS
ID : K24 MH114732
Pays : United States
Organisme : AHRQ HHS
ID : T32 HS000063
Pays : United States

Informations de copyright

Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

J.I.C. was supported by Agency for Healthcare Research and Quality grant number T32 HS000063 as part of the Harvard-wide Pediatric Health Services Research Fellowship Program. J.E.H. is a consultant for Merck. The other authors have no conflicts of interest to disclose.

Références

Mazurek GH, Jereb J, Lobue P, et al. Guidelines for using the QuantiFERON-TB Gold test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep. 2005;54:49–55.
American Academy of Pediatrics. Tuberculosis. Kimberlin DW, Brady MT, Jackson MA, Long SS, eds. In: Red Book: 2018 Report of the Committee on Infectious Diseases. 31st ed. Itasca, IL: American Academy of Pediatrics; 2018: pp. 829–853.
American Academy of Pediatrics. Tuberculosis. Kemberlin DW, Barnett ED, Lyfield R, Sawyer MH, eds. In: Red Book: 2021 Report of the Committee on Infectious Disease. Itisca, IL: American Academy of Pediatrics: 2021. pp 786–814.
Cruz AT, Reichman LB. The case for retiring the tuberculin skin test. Pediatrics. 2019;143:e20183327.
Ahmed A, Feng PI, Gaensbauer JT, et al.; Tuberculosis Epidemiologic Studies Consortium. Interferon-γ release assays in children <15 years of age. Pediatrics. 2020;145:e20191930.
Starke JR. Tuberculin skin test versus the interferon-γ release assays: out with the old, in with the new. Pediatrics. 2020;145:e20193021.
Goetzinger F, Burkhardt I, Villanueva P, et al. Interferon-gamma release assays have suboptimal sensitivity in both latent and active tuberculosis. Int J Tuberc Lung Dis. 2019;23:766–767.
Bonnewell JP, Farrow L, Dicks KV, et al. Geographic analysis of latent tuberculosis screening: a health system approach. PLoS One. 2020;15:e0242055.
Edozie RK, Lewis B, Lo S, et al. Changing Faces of Greater Boston. 2019. Available at: https://wwwbostonindicatorsorg/-/media/indicators/boston-indicators-reports/report-files/changing-faces-2019/indicators-changing-facesf2webpdf . Accessed October 26, 2021.
McQuaid CF, Vassall A, Cohen T, et al. The impact of COVID-19 on TB: a review of the data. Int J Tuberc Lung Dis. 2021;25:436–446.
Mandalakas AM, Highsmith HY, Harris NM, et al. T-SPOT.TB performance in routine pediatric practice in a low TB burden setting. Pediatr Infect Dis J. 2018;37:292–297.
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Auteurs

Jeffrey I Campbell (JI)

From the Division of Infectious Diseases.

Mary Tabatneck (M)

Department of Pediatrics.

Mingwei Sun (M)

Center for Research Information Technology, Boston Children's Hospital, Boston, Massachusetts.

Wei He (W)

Center for Research Information Science and Computing, Massachusetts General Hospital, Boston, Massachusetts.

Nicholas Musinguzi (N)

Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.

Bethany Hedt-Gauthier (B)

Department of Global Health and Social Medicine, Harvard Medical School.

Gabriella S Lamb (GS)

From the Division of Infectious Diseases.

Don Goldmann (D)

From the Division of Infectious Diseases.

Vishakha Sabharwal (V)

Division of Pediatric Infectious Diseases, Boston Medical Center, Boston, Massachusetts.

Thomas J Sandora (TJ)

From the Division of Infectious Diseases.

Jessica E Haberer (JE)

Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts.

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