Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside.

COVID-19 COVID-19 vaccines Cell- and tissue-based therapy Coronavirus Immunization Passive

Journal

Iranian journal of medical sciences
ISSN: 1735-3688
Titre abrégé: Iran J Med Sci
Pays: Iran
ID NLM: 8104374

Informations de publication

Date de publication:
11 2022
Historique:
received: 05 09 2021
revised: 17 11 2021
accepted: 10 12 2021
entrez: 16 11 2022
pubmed: 17 11 2022
medline: 19 11 2022
Statut: ppublish

Résumé

In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China. This virus rapidly spread worldwide and was declared a global pandemic by the World Health Organization (WHO) in March 2020. High incidence, long incubation period, and diverse clinical signs of the disease posed a huge challenge globally. The efforts of health systems have been focused on repurposing existing drugs or developing innovative therapies to reduce the morbidity and mortality associated with SARS-CoV-2. In addition, most of the large pharmaceutical companies are intensely working on vaccine development to swiftly deliver safe and effective vaccines to prevent further spread of the virus. In this review, we will discuss the latest data on therapeutic strategies undergoing clinical trials. Additionally, we will provide a summary of vaccines currently under development.

Identifiants

pubmed: 36380976
doi: 10.30476/IJMS.2021.92662.2396
pii: IJMS-47-6
pmc: PMC9652495
doi:

Substances chimiques

COVID-19 Vaccines 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

517-532

Informations de copyright

Copyright: © Iranian Journal of Medical Sciences.

Déclaration de conflit d'intérêts

None declared.

Références

Vaccines (Basel). 2019 Apr 24;7(2):
pubmed: 31022829
Virus Res. 2020 Oct 15;288:198114
pubmed: 32800805
Lancet Infect Dis. 2020 Apr;20(4):398-400
pubmed: 32113510
Chem Phys Lipids. 2021 Jan;234:105009
pubmed: 33189639
N Engl J Med. 2021 Feb 25;384(8):693-704
pubmed: 32678530
BMJ. 2020 May 14;369:m1849
pubmed: 32409561
Cureus. 2020 Aug 3;12(8):e9535
pubmed: 32905148
JAMA. 2021 Mar 9;325(10):1015
pubmed: 33544136
J Clin Invest. 2020 Jun 1;130(6):2757-2765
pubmed: 32254064
Cell. 2020 May 28;181(5):969-977
pubmed: 32437659
Lancet Infect Dis. 2021 Aug;21(8):1107-1119
pubmed: 33773111
Clin Infect Dis. 2021 Dec 6;73(11):e3996-e4004
pubmed: 33031500
J Infect. 2005 Aug;51(2):98-102
pubmed: 16038758
Nat Rev Microbiol. 2021 Jul;19(7):409-424
pubmed: 34075212
NPJ Vaccines. 2021 Aug 5;6(1):97
pubmed: 34354082
Stem Cell Res Ther. 2020 May 24;11(1):192
pubmed: 32448377
Am J Respir Crit Care Med. 2018 Mar 15;197(6):700-701
pubmed: 29227752
Biochemistry (Mosc). 2016 Jul;81(7):700-8
pubmed: 27449616
Trends Immunol. 2007 May;28(5):219-26
pubmed: 17400510
Front Immunol. 2020 Sep 17;11:564925
pubmed: 33072103
Lancet. 2021 May 01;397(10285):1637-1645
pubmed: 33933206
Lancet. 2020 Feb 29;395(10225):683-684
pubmed: 32122468
Biomed Pharmacother. 2021 May;137:111254
pubmed: 33550049
BMJ Open. 2021 Jun 24;11(6):e048416
pubmed: 34168031
Int J Antimicrob Agents. 2020 May;55(5):105938
pubmed: 32171740
Transfus Apher Sci. 2020 Jun;59(3):102790
pubmed: 32345485
Engineering (Beijing). 2020 Oct;6(10):1192-1198
pubmed: 32346491
Cells. 2020 Apr 09;9(4):
pubmed: 32283815
Am J Surg. 1995 Dec;170(6):591-5; discussion 595-6
pubmed: 7492007
J Virol. 2011 Dec;85(23):12201-15
pubmed: 21937658
Am J Reprod Immunol. 2012 Jan;67(1):1-8
pubmed: 21951555
Viruses. 2020 Feb 25;12(3):
pubmed: 32106567
Expert Opin Drug Discov. 2021 Dec;16(12):1403-1414
pubmed: 34304682
BMJ Open Respir Res. 2019 Jan 12;6(1):e000308
pubmed: 30713713
N Engl J Med. 2021 Mar 18;384(11):1015-1027
pubmed: 33523609
Thorax. 2004 Mar;59(3):252-6
pubmed: 14985565
Respir Res. 2014 Apr 04;15:39
pubmed: 24708472
Comput Struct Biotechnol J. 2021;19:2508-2517
pubmed: 33936564
Lancet Respir Med. 2021 Dec;9(12):1407-1418
pubmed: 34480861
Med J Aust. 2020 May;212(9):416-420
pubmed: 32266987
N Engl J Med. 2021 Sep 16;385(12):1147-1149
pubmed: 34407335
Open Forum Infect Dis. 2021 May 17;8(7):ofab254
pubmed: 34250192
Expert Rev Anti Infect Ther. 2017 May;15(5):483-492
pubmed: 28286997
Future Virol. 2021 Nov;:
pubmed: 34858516
Nat Commun. 2021 Mar 1;12(1):1346
pubmed: 33649323
JAMA. 2020 Jul 14;324(2):131-132
pubmed: 32539093
N Engl J Med. 2003 May 15;348(20):1995-2005
pubmed: 12671061
Eur J Pharmacol. 2021 Feb 5;892:173751
pubmed: 33245898
Virus Res. 2008 Apr;133(1):13-9
pubmed: 17374415
Eur Respir J. 2020 Apr 16;55(4):
pubmed: 32269085
Cochrane Database Syst Rev. 2020 Jul 10;7:CD013600
pubmed: 32648959
Expert Rev Vaccines. 2012 Dec;11(12):1405-13
pubmed: 23252385
N Engl J Med. 2021 Jul 29;385(5):406-415
pubmed: 34133856
J Pharm Pharm Sci. 2021;24:246-257
pubmed: 34048671
Aging Dis. 2020 Mar 9;11(2):216-228
pubmed: 32257537
J Virol. 2004 Nov;78(22):12672-6
pubmed: 15507655
N Engl J Med. 2021 Mar 4;384(9):795-807
pubmed: 33306283
BMJ. 2021 Aug 19;374:n1971
pubmed: 34413059
Lancet Infect Dis. 2020 Apr;20(4):400-402
pubmed: 32113509
Ann N Y Acad Sci. 2015 Sep;1351:114-26
pubmed: 26152292
Clin Infect Dis. 2020 Apr 15;70(9):1837-1844
pubmed: 31925415
Cell Mol Immunol. 2020 Jun;17(6):613-620
pubmed: 32203189
Ir J Med Sci. 2021 Nov;190(4):1637-1638
pubmed: 33433843
Nat Rev Drug Discov. 2018 Apr;17(4):261-279
pubmed: 29326426
J Autoimmun. 2020 May;109:102433
pubmed: 32113704
Virol J. 2005 Aug 22;2:69
pubmed: 16115318
Pharmacotherapy. 2020 May;40(5):416-437
pubmed: 32259313
Indian J Pharmacol. 2020 Jul-Aug;52(4):313-323
pubmed: 33078733
J Infect Chemother. 2021 Jun;27(6):876-881
pubmed: 33676844
Int J Antimicrob Agents. 2020 Mar;55(3):105923
pubmed: 32070753
Nat Commun. 2020 Jan 10;11(1):222
pubmed: 31924756
Antimicrob Agents Chemother. 2020 Nov 17;64(12):
pubmed: 32958718
Immunology. 2020 Jul;160(3):261-268
pubmed: 32460357
PeerJ. 2020 Jul 27;8:e9572
pubmed: 33194329
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Turk J Med Sci. 2020 Apr 17;50(SI-1):620-632
pubmed: 32299202
Signal Transduct Target Ther. 2020 Feb 21;5(1):18
pubmed: 32296012
PLoS One. 2012;7(4):e35421
pubmed: 22536382
Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9490-9496
pubmed: 32253318
Autoimmun Rev. 2020 Jul;19(7):102554
pubmed: 32380316
JAMA. 2020 Sep 15;324(11):1041-1042
pubmed: 32821934
Nat Biotechnol. 2021 Dec;39(12):1479-1482
pubmed: 34785814
Signal Transduct Target Ther. 2021 Jun 9;6(1):226
pubmed: 34108440
Hum Vaccin. 2011 Oct;7(10):999-1011
pubmed: 21941090
Intern Emerg Med. 2021 Aug;16(5):1395-1399
pubmed: 33856664
JAMA. 2020 May 12;323(18):1824-1836
pubmed: 32282022
Nat Commun. 2021 Apr 15;12(1):2349
pubmed: 33859192
Clin Pharmacol Ther. 2010 Apr;87(4):396-8
pubmed: 20305672
J Cardiovasc Pharmacol Ther. 2015 Jan;20(1):36-51
pubmed: 24938456
Mayo Clin Proc. 2021 May;96(5):1262-1275
pubmed: 33958057
N Engl J Med. 2020 Nov 5;383(19):1813-1826
pubmed: 32445440
Clin Epidemiol Glob Health. 2021 Jul-Sep;11:100755
pubmed: 33969237
J Clin Invest. 2021 Jul 1;131(13):
pubmed: 33974559
Hum Vaccin Immunother. 2014;10(3):778-96
pubmed: 24300669
Elife. 2021 Jun 04;10:
pubmed: 34085928
Lancet Infect Dis. 2003 Nov;3(11):722-7
pubmed: 14592603
Nat Commun. 2021 Jan 14;12(1):372
pubmed: 33446655
N Engl J Med. 2021 Apr 22;384(16):1503-1516
pubmed: 33631066
Clin Immunol. 2020 May;214:108393
pubmed: 32222466
Nat Rev Cardiol. 2020 May;17(5):259-260
pubmed: 32139904
J Infect Public Health. 2021 Jun;14(6):740-748
pubmed: 34020215
Stem Cell Rev Rep. 2021 Feb;17(1):163-175
pubmed: 32564256
Vaccine. 2021 Jan 15;39(3):457-459
pubmed: 33339671
Front Med (Lausanne). 2020 Apr 24;7:170
pubmed: 32391369

Auteurs

Banafshe Abadi (B)

Pharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Brain Cancer Research Core, Universal Scientific Education and Research Network, Tehran, Iran.

Amir Hossein Aarabi Jeshvaghani (AH)

Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.

Hadis Fathalipour (H)

Pharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.

Leili Dehghan (L)

Department of Pharmaceutical Biotechnology, School of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.

Kosar Rahimi Sirjani (K)

Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.

Hamid Forootanfar (H)

Pharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Department of Pharmaceutical Biotechnology, School of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.

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