Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review.

Aortic valve Cardiac surgery Cardiac tumors Sarcomas

Journal

European heart journal. Case reports
ISSN: 2514-2119
Titre abrégé: Eur Heart J Case Rep
Pays: England
ID NLM: 101730741

Informations de publication

Date de publication:
Nov 2022
Historique:
received: 09 12 2021
revised: 01 03 2022
accepted: 10 10 2022
entrez: 16 11 2022
pubmed: 17 11 2022
medline: 17 11 2022
Statut: epublish

Résumé

Malignant tumours of the aortic valve apparatus are extremely rare and difficult to diagnose. Their proximity to the coronary ostium may cause an acute coronary syndrome (ACS) either by infiltration or by embolization. We report a case of primary aortic valve undifferentiated sarcoma causing recurrent episodes of ACS, and we provide a literature review for primary cardiac valve tumours. This case also highlights the need for further evaluation of other causes of ACS in patients with minimal coronary artery disease risk factors and recurrent ACS. The majority of valve tumours are fibroelastomas. Sarcomas are rare and lead to poor outcomes.

Sections du résumé

Background UNASSIGNED
Malignant tumours of the aortic valve apparatus are extremely rare and difficult to diagnose. Their proximity to the coronary ostium may cause an acute coronary syndrome (ACS) either by infiltration or by embolization.
Case summary UNASSIGNED
We report a case of primary aortic valve undifferentiated sarcoma causing recurrent episodes of ACS, and we provide a literature review for primary cardiac valve tumours. This case also highlights the need for further evaluation of other causes of ACS in patients with minimal coronary artery disease risk factors and recurrent ACS.
Conclusions UNASSIGNED
The majority of valve tumours are fibroelastomas. Sarcomas are rare and lead to poor outcomes.

Identifiants

pubmed: 36381172
doi: 10.1093/ehjcr/ytac412
pii: ytac412
pmc: PMC9640299
doi:

Types de publication

Case Reports

Langues

eng

Pagination

ytac412

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.

Déclaration de conflit d'intérêts

Conflict of interest: None declared.

Références

Interact Cardiovasc Thorac Surg. 2005 Aug;4(4):311-5
pubmed: 17670419
J Cardiothorac Surg. 2016 Feb 19;11:31
pubmed: 26891966
Cardiovasc Pathol. 2008 Jan-Feb;17(1):55-9
pubmed: 18160061
J Am Coll Cardiol. 2018 Jul 10;72(2):202-227
pubmed: 29976295
Ann Thorac Surg. 1991 Nov;52(5):1127-31
pubmed: 1953134
J Heart Valve Dis. 2008 May;17(3):348-51
pubmed: 18592934
Mayo Clin Proc. 2020 Jan;95(1):136-156
pubmed: 31902409
J Thorac Cardiovasc Surg. 2022 Feb 1;:
pubmed: 35219517
Case Rep Med. 2017;2017:8539606
pubmed: 29333163

Auteurs

Martine Parent (M)

Cardiovascular Division, McGill University Health Center Montreal, Montreal, QC, Canada.

Kevin Lachapelle (K)

Cardiac Surgery Division, McGill University Health Center Montreal, Montreal, QC, Canada.

Badia Issa-Chergui (B)

Department of Pathology, McGill University Health Center Montreal, Montreal, QC, Canada.

Thierry Alcindor (T)

Oncology Division, McGill University Health Center Montreal, Montreal, QC, Canada.

Jacques Genest (J)

Cardiovascular Division, McGill University Health Center Montreal, Montreal, QC, Canada.

Negareh Mousavi (N)

Cardiovascular Division, McGill University Health Center Montreal, Montreal, QC, Canada.
Cardio-Oncology Program, McGill University Health Center Montreal, Montreal, QC, Canada.

Classifications MeSH