The evaluation of serum lipid profile and apolipoprotein C-1 in the Iranian patients of Oral Squamous Cell Carcinoma.
Oral squamous cell carcinoma
Serum ApoC1
Serum lipid profile
Journal
BioMedicine
ISSN: 2211-8020
Titre abrégé: Biomedicine (Taipei)
Pays: China (Republic : 1949- )
ID NLM: 101611451
Informations de publication
Date de publication:
2022
2022
Historique:
received:
07
01
2022
accepted:
06
04
2022
entrez:
16
11
2022
pubmed:
17
11
2022
medline:
17
11
2022
Statut:
epublish
Résumé
The key role of apolipoprotein C-1 (ApoC-1) is reported in breast, pancreas and lung cancer. However, no information is available on potential difference of ApoC-1 between OSCC patients and healthy individuals. This work aimed to examine the serum ApoC-1 level as well as lipid profile values between OSCC patients and healthy control groups. In this study, 44 blood samples from 22 OSCC patients and 22 healthy individuals were collected to determine the values of lipid profile and ApoC-1 concentration using colorimetric method and Enzyme-Linked Immunosorbent Assay (ELISA), respectively. A significant decrease in serum lipid profile and ApoC-1 concentration was observed between OSCC and healthy control groups (P = 0.001). Our results confirm the previous findings on the significant differences of lipid profile between OSCC and controls, also show the lower serum level of ApoC-1 in OSCC as compared to the controls. Future studies would further elaborate the association of ApoC-1 with OSCC.
Sections du résumé
Background
UNASSIGNED
The key role of apolipoprotein C-1 (ApoC-1) is reported in breast, pancreas and lung cancer. However, no information is available on potential difference of ApoC-1 between OSCC patients and healthy individuals. This work aimed to examine the serum ApoC-1 level as well as lipid profile values between OSCC patients and healthy control groups.
Material and methods
UNASSIGNED
In this study, 44 blood samples from 22 OSCC patients and 22 healthy individuals were collected to determine the values of lipid profile and ApoC-1 concentration using colorimetric method and Enzyme-Linked Immunosorbent Assay (ELISA), respectively.
Results
UNASSIGNED
A significant decrease in serum lipid profile and ApoC-1 concentration was observed between OSCC and healthy control groups (P = 0.001).
Conclusion
UNASSIGNED
Our results confirm the previous findings on the significant differences of lipid profile between OSCC and controls, also show the lower serum level of ApoC-1 in OSCC as compared to the controls. Future studies would further elaborate the association of ApoC-1 with OSCC.
Identifiants
pubmed: 36381193
doi: 10.37796/2211-8039.1349
pii: bmed-12-03-040
pmc: PMC9629403
doi:
Types de publication
Journal Article
Langues
eng
Pagination
40-47Informations de copyright
© the Author(s).
Déclaration de conflit d'intérêts
Conflict of interest The authors declare no competing interest.
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