Acute Leukemia Presenting in the Pediatric Orbit.
acute lymphoblastic leukemia (all)
acute myeloid leukemia (aml)
acute myeloid sarcoma
ocular symptoms
pediatrics ophthalmology
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
accepted:
06
09
2022
entrez:
16
11
2022
pubmed:
17
11
2022
medline:
17
11
2022
Statut:
epublish
Résumé
We present a case series to evaluate the clinical features of acute leukemia presenting with primary orbital manifestations. We undertook a retrospective case review of primary orbital presentations of acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL) over a 10-year period at two hospital sites (Hereford County Hospital and Leicester Royal Infirmary). Our case series included four patients - two with AML and two with ALL. Patients were young (mean age of four years and five months) at presentation, all with unilateral disease, and presented with orbital signs. Although there was some confusion with the diagnosis at the time of referral, a suspicion of malignancy was made rapidly once ophthalmic review was initiated. All four cases were diagnosed with the assistance of peripheral blood film and bone marrow biopsy, without the need for orbital biopsy. All four cases had resolution of the orbital mass and remain disease-free.
Identifiants
pubmed: 36381778
doi: 10.7759/cureus.29996
pmc: PMC9636987
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e29996Informations de copyright
Copyright © 2022, Gounder et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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